TY - JOUR
T1 - You Are What You Eat: Application of Metabolomics Approaches to Advance Nutrition Research
AU - Emwas, Abdul-Hamid M.
AU - Al-Rifai, Nahla
AU - Szczepski, Kacper
AU - Alsuhaymi, Shuruq
AU - Rayyan, Saleh
AU - Almahasheer, Hanan
AU - Jaremko, Mariusz
AU - Brennan, Lorraine
AU - Lachowicz, Joanna Izabela
N1 - KAUST Repository Item: Exported on 2021-11-22
Acknowledgements: This research received no external funding.
PY - 2021/5/31
Y1 - 2021/5/31
N2 - A healthy condition is defined by complex human metabolic pathways that only function properly when fully satisfied by nutritional inputs. Poor nutritional intakes are associated with a number of metabolic diseases, such as diabetes, obesity, atherosclerosis, hypertension, and osteoporosis. In recent years, nutrition science has undergone an extraordinary transformation driven by the development of innovative software and analytical platforms. However, the complexity and variety of the chemical components present in different food types, and the diversity of interactions in the biochemical networks and biological systems, makes nutrition research a complicated field. Metabolomics science is an “-omic”, joining proteomics, transcriptomics, and genomics in affording a global understanding of biological systems. In this review, we present the main metabolomics approaches, and highlight the applications and the potential for metabolomics approaches in advancing nutritional food research.
AB - A healthy condition is defined by complex human metabolic pathways that only function properly when fully satisfied by nutritional inputs. Poor nutritional intakes are associated with a number of metabolic diseases, such as diabetes, obesity, atherosclerosis, hypertension, and osteoporosis. In recent years, nutrition science has undergone an extraordinary transformation driven by the development of innovative software and analytical platforms. However, the complexity and variety of the chemical components present in different food types, and the diversity of interactions in the biochemical networks and biological systems, makes nutrition research a complicated field. Metabolomics science is an “-omic”, joining proteomics, transcriptomics, and genomics in affording a global understanding of biological systems. In this review, we present the main metabolomics approaches, and highlight the applications and the potential for metabolomics approaches in advancing nutritional food research.
UR - http://hdl.handle.net/10754/669323
UR - https://www.mdpi.com/2304-8158/10/6/1249
UR - http://www.scopus.com/inward/record.url?scp=85107800440&partnerID=8YFLogxK
U2 - 10.3390/foods10061249
DO - 10.3390/foods10061249
M3 - Article
C2 - 34072780
SN - 2304-8158
VL - 10
SP - 1249
JO - Foods
JF - Foods
IS - 6
ER -
