Abstract
Manipulation of cellular identity in the laboratory is generally inefficient due to stochastic events, including epigenomic alterations. Recently in Science, Zuryn etal. (2014) demonstrate that the efficiency of a naturally occurring transdifferentiation event in Caenorhabditis elegans is ensured through stepwise epigenetic modifications during specific phases of lineage conversion.
Original language | English (US) |
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Pages (from-to) | 641-642 |
Number of pages | 2 |
Journal | Developmental Cell |
Volume | 30 |
Issue number | 6 |
DOIs | |
State | Published - Sep 29 2014 |
Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2014 Elsevier Inc.
ASJC Scopus subject areas
- Molecular Biology
- General Biochemistry, Genetics and Molecular Biology
- Developmental Biology
- Cell Biology