Bayesian disease mapping, yet if undeniably useful to describe variation in risk over time and space, comes with the hurdle of prior elicitation on hard-to-interpret random effect precision parameters. We introduce a reparametrized version of the popular spatio-temporal interaction models, based on Kronecker product intrinsic Gaussian Markov Random Fields, that we name the variance partitioning (VP) model. The VP model includes a mixing parameter that balances the contribution of the main and interaction effects to the total (generalized) variance and enhances interpretability. The use of a penalized complexity prior on the mixing parameter aids in coding prior information in a intuitive way. We illustrate the advantages of the VP model using two case studies.
|Original language||English (US)|
|Journal||Accepted for publication in Statistical Methods in Medical Research|
|State||Published - 2022|