Translational and post-translational regulation of polyamine metabolic enzymes in plants.

J F Jiménez-Bremont; A I Chávez-Martínez; M A Ortega-Amaro; M L Guerrero-González; F I Jasso-Robles; Israel Maruri Lopez; Ji-Hong Liu; Sarvajeet Singh Gill; M Rodríguez-Kessler

doi:10.1016/j.jbiotec.2021.12.004

Translational and post-translational regulation of polyamine metabolic enzymes in plants.

J F Jiménez-Bremont, A I Chávez-Martínez, M A Ortega-Amaro, M L Guerrero-González, F I Jasso-Robles, Israel Maruri Lopez, Ji-Hong Liu, Sarvajeet Singh Gill, M Rodríguez-Kessler

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Polyamines are small organic and basic polycations that perform essential regulatory functions in all living organisms. Fluctuations in polyamine content have been observed to occur during growth, development and under stress conditions, implying that polyamines play pivotal roles in diverse cellular and physiological processes. To achieve polyamine homeostasis, the entire metabolic pathway is subjected to a fine-tuned regulation of its biosynthetic and catabolic genes and enzymes. In this review, we describe and discuss the most important mechanisms implicated in the translational and post-translational regulation of polyamine metabolic enzymes in plants. At the translational level, we emphasize the role of polyamines in the modulation of upstream open reading frame (uORF) activities that control the translation of polyamine biosynthetic and catabolic mRNAs. At the post-translational level, different aspects of the regulation of polyamine metabolic proteins are depicted, such as the proteolytic activation of enzyme precursors, the importance of dimerization in protein stability as well as in protein intracellular localization.

Original language	English (US)
Pages (from-to)	1-10
Number of pages	10
Journal	Journal of Biotechnology
Volume	344
DOIs	https://doi.org/10.1016/j.jbiotec.2021.12.004
State	Published - Dec 16 2021

Bibliographical note

KAUST Repository Item: Exported on 2022-01-27
Acknowledgements: This study was financed by Investigación Ciencia Básica CONACYT-México (2015-256574; 2017-2018-A1-S-25233), Ciencia de Frontera CONACYT-México (2019-1564453), National Key Research and Development Program of China (2018YFD1000302) and the National Natural Science Foundation of China (31772273). We apologize to those colleagues whose relevant work were not cited due to space constraints. We thank to Dr. Michael Frederick Dunn for his critical and grammatical review.

ASJC Scopus subject areas

Applied Microbiology and Biotechnology
Biotechnology

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10.1016/j.jbiotec.2021.12.004

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@article{ac144cab92c14f28b5d849956fd957da,

title = "Translational and post-translational regulation of polyamine metabolic enzymes in plants.",

abstract = "Polyamines are small organic and basic polycations that perform essential regulatory functions in all living organisms. Fluctuations in polyamine content have been observed to occur during growth, development and under stress conditions, implying that polyamines play pivotal roles in diverse cellular and physiological processes. To achieve polyamine homeostasis, the entire metabolic pathway is subjected to a fine-tuned regulation of its biosynthetic and catabolic genes and enzymes. In this review, we describe and discuss the most important mechanisms implicated in the translational and post-translational regulation of polyamine metabolic enzymes in plants. At the translational level, we emphasize the role of polyamines in the modulation of upstream open reading frame (uORF) activities that control the translation of polyamine biosynthetic and catabolic mRNAs. At the post-translational level, different aspects of the regulation of polyamine metabolic proteins are depicted, such as the proteolytic activation of enzyme precursors, the importance of dimerization in protein stability as well as in protein intracellular localization.",

author = "Jim{\'e}nez-Bremont, {J F} and Ch{\'a}vez-Mart{\'i}nez, {A I} and Ortega-Amaro, {M A} and Guerrero-Gonz{\'a}lez, {M L} and Jasso-Robles, {F I} and {Maruri Lopez}, Israel and Ji-Hong Liu and Gill, {Sarvajeet Singh} and M Rodr{\'i}guez-Kessler",

note = "KAUST Repository Item: Exported on 2022-01-27 Acknowledgements: This study was financed by Investigaci{\'o}n Ciencia B{\'a}sica CONACYT-M{\'e}xico (2015-256574; 2017-2018-A1-S-25233), Ciencia de Frontera CONACYT-M{\'e}xico (2019-1564453), National Key Research and Development Program of China (2018YFD1000302) and the National Natural Science Foundation of China (31772273). We apologize to those colleagues whose relevant work were not cited due to space constraints. We thank to Dr. Michael Frederick Dunn for his critical and grammatical review.",

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doi = "10.1016/j.jbiotec.2021.12.004",

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AU - Jiménez-Bremont, J F

AU - Chávez-Martínez, A I

AU - Ortega-Amaro, M A

AU - Guerrero-González, M L

AU - Jasso-Robles, F I

AU - Maruri Lopez, Israel

AU - Liu, Ji-Hong

AU - Gill, Sarvajeet Singh

AU - Rodríguez-Kessler, M

N1 - KAUST Repository Item: Exported on 2022-01-27 Acknowledgements: This study was financed by Investigación Ciencia Básica CONACYT-México (2015-256574; 2017-2018-A1-S-25233), Ciencia de Frontera CONACYT-México (2019-1564453), National Key Research and Development Program of China (2018YFD1000302) and the National Natural Science Foundation of China (31772273). We apologize to those colleagues whose relevant work were not cited due to space constraints. We thank to Dr. Michael Frederick Dunn for his critical and grammatical review.

PY - 2021/12/16

Y1 - 2021/12/16

N2 - Polyamines are small organic and basic polycations that perform essential regulatory functions in all living organisms. Fluctuations in polyamine content have been observed to occur during growth, development and under stress conditions, implying that polyamines play pivotal roles in diverse cellular and physiological processes. To achieve polyamine homeostasis, the entire metabolic pathway is subjected to a fine-tuned regulation of its biosynthetic and catabolic genes and enzymes. In this review, we describe and discuss the most important mechanisms implicated in the translational and post-translational regulation of polyamine metabolic enzymes in plants. At the translational level, we emphasize the role of polyamines in the modulation of upstream open reading frame (uORF) activities that control the translation of polyamine biosynthetic and catabolic mRNAs. At the post-translational level, different aspects of the regulation of polyamine metabolic proteins are depicted, such as the proteolytic activation of enzyme precursors, the importance of dimerization in protein stability as well as in protein intracellular localization.

AB - Polyamines are small organic and basic polycations that perform essential regulatory functions in all living organisms. Fluctuations in polyamine content have been observed to occur during growth, development and under stress conditions, implying that polyamines play pivotal roles in diverse cellular and physiological processes. To achieve polyamine homeostasis, the entire metabolic pathway is subjected to a fine-tuned regulation of its biosynthetic and catabolic genes and enzymes. In this review, we describe and discuss the most important mechanisms implicated in the translational and post-translational regulation of polyamine metabolic enzymes in plants. At the translational level, we emphasize the role of polyamines in the modulation of upstream open reading frame (uORF) activities that control the translation of polyamine biosynthetic and catabolic mRNAs. At the post-translational level, different aspects of the regulation of polyamine metabolic proteins are depicted, such as the proteolytic activation of enzyme precursors, the importance of dimerization in protein stability as well as in protein intracellular localization.

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JO - Journal of Biotechnology

JF - Journal of Biotechnology

ER -

Translational and post-translational regulation of polyamine metabolic enzymes in plants.

Abstract

Bibliographical note

ASJC Scopus subject areas

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