TiPs: a database of therapeutic targets in pathogens and associated tools.

Rosalba Lepore; Anna Tramontano; Allegra Via

doi:10.1093/bioinformatics/btt289

TiPs: a database of therapeutic targets in pathogens and associated tools.

Rosalba Lepore, Anna Tramontano, Allegra Via

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

MOTIVATION: The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes. AVAILABILITY AND IMPLEMENTATION: The TiPs database is freely available at http://biocomputing.it/tips. CONTACT: [email protected] or [email protected].

Original language	English (US)
Pages (from-to)	1821-1822
Number of pages	2
Journal	Bioinformatics
Volume	29
Issue number	14
DOIs	https://doi.org/10.1093/bioinformatics/btt289
State	Published - May 21 2013
Externally published	Yes

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledged KAUST grant number(s): KUK-I1-012-43
Acknowledgements: Funding: This work was supported by the King Abdullah University of Science and Technology (KAUST), Award No. KUK-I1-012-43, PRIN 20108XYHJS and FIRB RBIN06E9Z8_005.
This publication acknowledges KAUST support, but has no KAUST affiliated authors.

Access to Document

10.1093/bioinformatics/btt289

https://repository.kaust.edu.sa/bitstream/10754/596827/1/PMC3702258.pdf

Cite this

@article{3a10c19baf8947bca9815cc08aa47341,

title = "TiPs: a database of therapeutic targets in pathogens and associated tools.",

abstract = "MOTIVATION: The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes. AVAILABILITY AND IMPLEMENTATION: The TiPs database is freely available at http://biocomputing.it/tips. CONTACT: [email protected] or [email protected].",

author = "Rosalba Lepore and Anna Tramontano and Allegra Via",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledged KAUST grant number(s): KUK-I1-012-43 Acknowledgements: Funding: This work was supported by the King Abdullah University of Science and Technology (KAUST), Award No. KUK-I1-012-43, PRIN 20108XYHJS and FIRB RBIN06E9Z8_005. This publication acknowledges KAUST support, but has no KAUST affiliated authors.",

year = "2013",

month = may,

day = "21",

doi = "10.1093/bioinformatics/btt289",

language = "English (US)",

volume = "29",

pages = "1821--1822",

journal = "Bioinformatics",

issn = "1367-4803",

publisher = "Oxford University Press",

number = "14",

}

TY - JOUR

T1 - TiPs: a database of therapeutic targets in pathogens and associated tools.

AU - Lepore, Rosalba

AU - Tramontano, Anna

AU - Via, Allegra

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledged KAUST grant number(s): KUK-I1-012-43 Acknowledgements: Funding: This work was supported by the King Abdullah University of Science and Technology (KAUST), Award No. KUK-I1-012-43, PRIN 20108XYHJS and FIRB RBIN06E9Z8_005. This publication acknowledges KAUST support, but has no KAUST affiliated authors.

PY - 2013/5/21

Y1 - 2013/5/21

N2 - MOTIVATION: The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes. AVAILABILITY AND IMPLEMENTATION: The TiPs database is freely available at http://biocomputing.it/tips. CONTACT: [email protected] or [email protected].

AB - MOTIVATION: The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes. AVAILABILITY AND IMPLEMENTATION: The TiPs database is freely available at http://biocomputing.it/tips. CONTACT: [email protected] or [email protected].

UR - http://hdl.handle.net/10754/596827

UR - https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btt289

UR - http://www.scopus.com/inward/record.url?scp=84880205892&partnerID=8YFLogxK

U2 - 10.1093/bioinformatics/btt289

DO - 10.1093/bioinformatics/btt289

M3 - Article

C2 - 23698860

SN - 1367-4803

VL - 29

SP - 1821

EP - 1822

JO - Bioinformatics

JF - Bioinformatics

IS - 14

ER -

TiPs: a database of therapeutic targets in pathogens and associated tools.

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this