Tip60-ing the balance in DSB repair

Wolfgang Fischle

doi:10.1038/ncb1109-1279

Tip60-ing the balance in DSB repair

Wolfgang Fischle^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The tumour suppressor Tip60 is a histone acetyltransferase implicated in transcriptional control and DNA double-strand break repair. Tip60 binds to the heterochromatic histone mark H3K9me3, triggering acetylation and activation of DNA double-strand break repair factors.

Original language	English (US)
Pages (from-to)	1279-1281
Number of pages	3
Journal	Nature Cell Biology
Volume	11
Issue number	11
DOIs	https://doi.org/10.1038/ncb1109-1279
State	Published - 2009
Externally published	Yes

ASJC Scopus subject areas

Cell Biology

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title = "Tip60-ing the balance in DSB repair",

abstract = "The tumour suppressor Tip60 is a histone acetyltransferase implicated in transcriptional control and DNA double-strand break repair. Tip60 binds to the heterochromatic histone mark H3K9me3, triggering acetylation and activation of DNA double-strand break repair factors.",

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Tip60-ing the balance in DSB repair

Abstract

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