@inproceedings{8751254dbddc4596b09d1d96a565069f,
title = "Tiamat: A three-dimensional editing tool for complex DNA structures",
abstract = "We present the development of a new graphical user interface driven molecular modeling, editing and visualization tool called Tiamat. Tiamat addresses the challenge of how to efficiently model large and complex DNA nanostructures. We describe the three major components of our system. First, we discuss design guidelines and data structures that form the basis of flexible and large-scale editing. Second, we explain a semi-automatic sequence generator that combines user input with random sequence generation to efficiently label the molecules in the DNA structure. Third, we outline the visualization techniques including a simplification algorithm that are used to render large designs. The results demonstrate how Tiamat was used to generate large and complex designs.",
keywords = "3D DNA structure display, DNA sequence design, DNA tile, Structural DNA nanotechnology",
author = "Sean Williams and Kyle Lund and Chenxiang Lin and Peter Wonka and Stuart Lindsay and Hao Yan",
year = "2009",
doi = "10.1007/978-3-642-03076-5_8",
language = "English (US)",
isbn = "3642030750",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
pages = "90--101",
booktitle = "DNA Computing - 14th International Meeting on DNA Computing, DNA14, Revised Selected Papers",
note = "14th International Meeting on DNA Computing, DNA14 ; Conference date: 02-06-2008 Through 09-06-2008",
}