The wheat powdery mildew resistance gene Pm4 also confers resistance to wheat blast

Tom O’Hara; Andrew Steed; Rachel Goddard; Kumar Gaurav; Sanu Arora; Jesús Quiroz-Chávez; Ricardo Ramírez-González; Roshani Badgami; David Gilbert; Javier Sánchez-Martín; Luzie Wingen; Cong Feng; Mei Jiang; Shifeng Cheng; Susanne Dreisigacker; Beat Keller; Brande B.H. Wulff; Cristóbal Uauy; Paul Nicholson

doi:10.1038/s41477-024-01718-8

The wheat powdery mildew resistance gene Pm4 also confers resistance to wheat blast

Tom O’Hara, Andrew Steed, Rachel Goddard, Kumar Gaurav, Sanu Arora, Jesús Quiroz-Chávez, Ricardo Ramírez-González, Roshani Badgami, David Gilbert, Javier Sánchez-Martín, Luzie Wingen, Cong Feng, Mei Jiang, Shifeng Cheng, Susanne Dreisigacker, Beat Keller, Brande B.H. Wulff, Cristóbal Uauy, Paul Nicholson^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Wheat blast, caused by the fungus Magnaporthe oryzae, threatens global cereal production since its emergence in Brazil in 1985 and recently spread to Bangladesh and Zambia. Here we demonstrate that the AVR-Rmg8 effector, common in wheat-infecting isolates, is recognized by the gene Pm4, previously shown to confer resistance to specific races of Blumeria graminis f. sp. tritici, the cause of powdery mildew of wheat. We show that Pm4 alleles differ in their recognition of different AVR-Rmg8 alleles, and some confer resistance only in seedling leaves but not spikes, making it important to select for those alleles that function in both tissues. This study has identified a gene recognizing an important virulence factor present in wheat blast isolates in Bangladesh and Zambia and represents an important first step towards developing durably resistant wheat cultivars for these regions.

Original language	English (US)
Pages (from-to)	984-993
Number of pages	10
Journal	Nature Plants
Volume	10
Issue number	6
DOIs	https://doi.org/10.1038/s41477-024-01718-8
State	Published - Jun 2024

Bibliographical note

Publisher Copyright:
© The Author(s) 2024.

ASJC Scopus subject areas

Plant Science

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O’Hara, T., Steed, A., Goddard, R., Gaurav, K., Arora, S., Quiroz-Chávez, J., Ramírez-González, R., Badgami, R., Gilbert, D., Sánchez-Martín, J., Wingen, L., Feng, C., Jiang, M., Cheng, S., Dreisigacker, S., Keller, B., Wulff, B. B. H., Uauy, C., & Nicholson, P. (2024). The wheat powdery mildew resistance gene Pm4 also confers resistance to wheat blast. Nature Plants, 10(6), 984-993. https://doi.org/10.1038/s41477-024-01718-8

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title = "The wheat powdery mildew resistance gene Pm4 also confers resistance to wheat blast",

abstract = "Wheat blast, caused by the fungus Magnaporthe oryzae, threatens global cereal production since its emergence in Brazil in 1985 and recently spread to Bangladesh and Zambia. Here we demonstrate that the AVR-Rmg8 effector, common in wheat-infecting isolates, is recognized by the gene Pm4, previously shown to confer resistance to specific races of Blumeria graminis f. sp. tritici, the cause of powdery mildew of wheat. We show that Pm4 alleles differ in their recognition of different AVR-Rmg8 alleles, and some confer resistance only in seedling leaves but not spikes, making it important to select for those alleles that function in both tissues. This study has identified a gene recognizing an important virulence factor present in wheat blast isolates in Bangladesh and Zambia and represents an important first step towards developing durably resistant wheat cultivars for these regions.",

author = "Tom O{\textquoteright}Hara and Andrew Steed and Rachel Goddard and Kumar Gaurav and Sanu Arora and Jes{\'u}s Quiroz-Ch{\'a}vez and Ricardo Ram{\'i}rez-Gonz{\'a}lez and Roshani Badgami and David Gilbert and Javier S{\'a}nchez-Mart{\'i}n and Luzie Wingen and Cong Feng and Mei Jiang and Shifeng Cheng and Susanne Dreisigacker and Beat Keller and Wulff, {Brande B.H.} and Crist{\'o}bal Uauy and Paul Nicholson",

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doi = "10.1038/s41477-024-01718-8",

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O’Hara, T, Steed, A, Goddard, R, Gaurav, K, Arora, S, Quiroz-Chávez, J, Ramírez-González, R, Badgami, R, Gilbert, D, Sánchez-Martín, J, Wingen, L, Feng, C, Jiang, M, Cheng, S, Dreisigacker, S, Keller, B, Wulff, BBH, Uauy, C & Nicholson, P 2024, 'The wheat powdery mildew resistance gene Pm4 also confers resistance to wheat blast', Nature Plants, vol. 10, no. 6, pp. 984-993. https://doi.org/10.1038/s41477-024-01718-8

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AU - Steed, Andrew

AU - Goddard, Rachel

AU - Gaurav, Kumar

AU - Arora, Sanu

AU - Quiroz-Chávez, Jesús

AU - Ramírez-González, Ricardo

AU - Badgami, Roshani

AU - Gilbert, David

AU - Sánchez-Martín, Javier

AU - Wingen, Luzie

AU - Feng, Cong

AU - Jiang, Mei

AU - Cheng, Shifeng

AU - Dreisigacker, Susanne

AU - Keller, Beat

AU - Wulff, Brande B.H.

AU - Uauy, Cristóbal

AU - Nicholson, Paul

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AB - Wheat blast, caused by the fungus Magnaporthe oryzae, threatens global cereal production since its emergence in Brazil in 1985 and recently spread to Bangladesh and Zambia. Here we demonstrate that the AVR-Rmg8 effector, common in wheat-infecting isolates, is recognized by the gene Pm4, previously shown to confer resistance to specific races of Blumeria graminis f. sp. tritici, the cause of powdery mildew of wheat. We show that Pm4 alleles differ in their recognition of different AVR-Rmg8 alleles, and some confer resistance only in seedling leaves but not spikes, making it important to select for those alleles that function in both tissues. This study has identified a gene recognizing an important virulence factor present in wheat blast isolates in Bangladesh and Zambia and represents an important first step towards developing durably resistant wheat cultivars for these regions.

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The wheat powdery mildew resistance gene Pm4 also confers resistance to wheat blast

Abstract

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