The SAM kinase pathway: An integrated circuit for stress signaling in plants

Irute Meskiene; Wilco Ligterink; Laszlo Bögre; Claudia Jonak; Stefan Kiegerl; Judit Balog; Staffan Eklöf; Gustav Ammerer; Heribert Hirt

The SAM kinase pathway: An integrated circuit for stress signaling in plants

Irute Meskiene, Wilco Ligterink, Laszlo Bögre, Claudia Jonak, Stefan Kiegerl, Judit Balog, Staffan Eklöf, Gustav Ammerer, Heribert Hirt^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Mitogen-activated protein (MAP) kinases are universal transducers of extracellular signals in all eukaryotes. Multiple MAPK pathways exist in each organism that are differentially activated by a variety of stimuli including chemical as well as physical factors. We have characterized the stress-activated MAP kinase (SAMK) pathway in plants that is involved in mediating touch, drought, cold, and wounding. The SAMK pathway is activated by a posttranslational mechanism, but inactivation requires de novo expression of gene(s). One of these genes is MP2C encoding a protein phosphatase type 2C that is able to inactivate the SAMK pathway. MP2C expression itself is regulated by the SAMK pathway and constitutes a negative feedback mechanism for resetting the pathway.

Original language	English (US)
Pages (from-to)	339-344
Number of pages	6
Journal	Journal of Plant Research
Volume	111
Issue number	1102
State	Published - Jun 1998
Externally published	Yes

Keywords

Map kinase
Protein phosphatase 2c
Signal transduction
Stress

ASJC Scopus subject areas

Plant Science

Cite this

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title = "The SAM kinase pathway: An integrated circuit for stress signaling in plants",

abstract = "Mitogen-activated protein (MAP) kinases are universal transducers of extracellular signals in all eukaryotes. Multiple MAPK pathways exist in each organism that are differentially activated by a variety of stimuli including chemical as well as physical factors. We have characterized the stress-activated MAP kinase (SAMK) pathway in plants that is involved in mediating touch, drought, cold, and wounding. The SAMK pathway is activated by a posttranslational mechanism, but inactivation requires de novo expression of gene(s). One of these genes is MP2C encoding a protein phosphatase type 2C that is able to inactivate the SAMK pathway. MP2C expression itself is regulated by the SAMK pathway and constitutes a negative feedback mechanism for resetting the pathway.",

keywords = "Map kinase, Protein phosphatase 2c, Signal transduction, Stress",

author = "Irute Meskiene and Wilco Ligterink and Laszlo B{\"o}gre and Claudia Jonak and Stefan Kiegerl and Judit Balog and Staffan Ekl{\"o}f and Gustav Ammerer and Heribert Hirt",

year = "1998",

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language = "English (US)",

volume = "111",

pages = "339--344",

journal = "Journal of Plant Research",

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TY - JOUR

T1 - The SAM kinase pathway

T2 - An integrated circuit for stress signaling in plants

AU - Meskiene, Irute

AU - Ligterink, Wilco

AU - Bögre, Laszlo

AU - Jonak, Claudia

AU - Kiegerl, Stefan

AU - Balog, Judit

AU - Eklöf, Staffan

AU - Ammerer, Gustav

AU - Hirt, Heribert

PY - 1998/6

Y1 - 1998/6

N2 - Mitogen-activated protein (MAP) kinases are universal transducers of extracellular signals in all eukaryotes. Multiple MAPK pathways exist in each organism that are differentially activated by a variety of stimuli including chemical as well as physical factors. We have characterized the stress-activated MAP kinase (SAMK) pathway in plants that is involved in mediating touch, drought, cold, and wounding. The SAMK pathway is activated by a posttranslational mechanism, but inactivation requires de novo expression of gene(s). One of these genes is MP2C encoding a protein phosphatase type 2C that is able to inactivate the SAMK pathway. MP2C expression itself is regulated by the SAMK pathway and constitutes a negative feedback mechanism for resetting the pathway.

AB - Mitogen-activated protein (MAP) kinases are universal transducers of extracellular signals in all eukaryotes. Multiple MAPK pathways exist in each organism that are differentially activated by a variety of stimuli including chemical as well as physical factors. We have characterized the stress-activated MAP kinase (SAMK) pathway in plants that is involved in mediating touch, drought, cold, and wounding. The SAMK pathway is activated by a posttranslational mechanism, but inactivation requires de novo expression of gene(s). One of these genes is MP2C encoding a protein phosphatase type 2C that is able to inactivate the SAMK pathway. MP2C expression itself is regulated by the SAMK pathway and constitutes a negative feedback mechanism for resetting the pathway.

KW - Map kinase

KW - Protein phosphatase 2c

KW - Signal transduction

KW - Stress

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M3 - Article

SN - 0918-9440

VL - 111

SP - 339

EP - 344

JO - Journal of Plant Research

JF - Journal of Plant Research

IS - 1102

ER -

The SAM kinase pathway: An integrated circuit for stress signaling in plants

Abstract

Keywords

ASJC Scopus subject areas

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