The relationship between inflammatory markers and the risk of lung cancer: a prospective cohort study

G. Wang, L. P. Wei, N. Li, W. G. Xu, K. Su, F. Li, F. W. Tan, Z. Y. Lyu, X. S. Feng, X. Li, H. D. Chen, Y. H. Chen, L. W. Guo, H. Cui, P. F. Jiao, H. X. Liu, J. S. Ren, S. L. Wu, J. F. Shi, M. DaiJ. He

Research output: Contribution to journalArticlepeer-review

Abstract

目的: 探讨C-反应蛋白(CRP)和中性粒细胞(NE)与肺癌发病风险的关联性。 方法: 利用2006—2007年以开滦(集团)有限责任公司全体在职及退休职工为研究对象建立的开滦队列,随访至2015年12月,收集肺癌新发病例资料,采用多因素Cox比例风险模型评估基线CRP和NE水平与肺癌发病风险的关系。 结果: 92 735人被纳入研究,随访期间共新发肺癌850例。依据基线CRP和NE水平,将研究人群分为CRP≤3 mg/L且NE≤4×10(9)/L组(A组)、CRP≤3 mg/L且NE>4×10(9)/L组(B组)、CRP>3 mg/L且NE≤4×10(9)/L组(C组)和CRP>3 mg/L且NE>4×10(9)/L组(D组)。4组肺癌累积发病率分别为950/10万、1 030/10万、1 081/10万和1 596/10万,差异有统计学意义(P
Original languageEnglish (US)
Pages (from-to)633-637
Number of pages5
JournalZhonghua zhong liu za zhi [Chinese journal of oncology]
Volume41
Issue number8
DOIs
StatePublished - Aug 23 2019
Externally publishedYes

Bibliographical note

Generated from Scopus record by KAUST IRTS on 2023-09-21

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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