The genomes of 204 Vitis vinifera accessions reveal the origin of European wine grapes.

Gabriele Magris; Irena Jurman; Alice Fornasiero; Eleonora Paparelli; Rachel Schwope; Fabio Marroni; Gabriele Di Gaspero; Michele Morgante

doi:10.1038/s41467-021-27487-y

The genomes of 204 Vitis vinifera accessions reveal the origin of European wine grapes.

Gabriele Magris, Irena Jurman, Alice Fornasiero, Eleonora Paparelli, Rachel Schwope, Fabio Marroni, Gabriele Di Gaspero, Michele Morgante

Biological, Environmental Sciences and Engineering

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

In order to elucidate the still controversial processes that originated European wine grapes from its wild progenitor, here we analyse 204 genomes of Vitis vinifera and show that all analyses support a single domestication event that occurred in Western Asia and was followed by numerous and pervasive introgressions from European wild populations. This admixture generated the so-called international wine grapes that have diffused from Alpine countries worldwide. Across Europe, marked differences in genomic diversity are observed in local varieties that are traditionally cultivated in different wine producing countries, with Italy and France showing the largest diversity. Three genomic regions of reduced genetic diversity are observed, presumably as a consequence of artificial selection. In the lowest diversity region, two candidate genes that gained berry-specific expression in domesticated varieties may contribute to the change in berry size and morphology that makes the fruit attractive for human consumption and adapted for winemaking.

Original language	English (US)
Journal	Nature communications
Volume	12
Issue number	1
DOIs	https://doi.org/10.1038/s41467-021-27487-y
State	Published - Dec 21 2021

Bibliographical note

KAUST Repository Item: Exported on 2022-01-27
Acknowledgements: We thank the grape germplasm repositories of Consiglio per la Ricerca in agricoltura e l’analisi dell’Economia Agraria (CREA), Italy; Institut national de la recherche agrono-mique (INRA), Unité Expérimentale du Domaine de Vassal, France; Julius Kuhn Institute, Germany; Kmetijsko Gozdarski Zavod Nova Gorica, Slovenia; and Vivai Cooperativi Rauscedo (VCR) Research Center, Italy, Italy for plant material. We also thank Goran Zdunić and Andrey Zvyagin for sharing DNA samples; Paolo Sivilotti for discussions on the variety Berzamino, Andrea Bertoli, Mara Miculan and Nicoletta Felice for DNA and RNA library preparation. This work was supported by FP7–IDEAS–ERC “Novabreed” (grant agreement no. 294780, M.M.), by the Italian Ministry of Agriculture (project Vigneto, M.M.), and by the European Regional Development Fund, Interreg Italy–Slovenia Programme 2007–2013 (grant no 081-3/2011, project VISO, G.D.G.).

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Chemistry
General Physics and Astronomy

Access to Document

10.1038/s41467-021-27487-y

https://repository.kaust.edu.sa/bitstream/10754/675155/1/s41467-021-27487-y.pdf

Cite this

@article{266b8dc380e642a49b445e50cd807268,

title = "The genomes of 204 Vitis vinifera accessions reveal the origin of European wine grapes.",

abstract = "In order to elucidate the still controversial processes that originated European wine grapes from its wild progenitor, here we analyse 204 genomes of Vitis vinifera and show that all analyses support a single domestication event that occurred in Western Asia and was followed by numerous and pervasive introgressions from European wild populations. This admixture generated the so-called international wine grapes that have diffused from Alpine countries worldwide. Across Europe, marked differences in genomic diversity are observed in local varieties that are traditionally cultivated in different wine producing countries, with Italy and France showing the largest diversity. Three genomic regions of reduced genetic diversity are observed, presumably as a consequence of artificial selection. In the lowest diversity region, two candidate genes that gained berry-specific expression in domesticated varieties may contribute to the change in berry size and morphology that makes the fruit attractive for human consumption and adapted for winemaking.",

author = "Gabriele Magris and Irena Jurman and Alice Fornasiero and Eleonora Paparelli and Rachel Schwope and Fabio Marroni and {Di Gaspero}, Gabriele and Michele Morgante",

note = "KAUST Repository Item: Exported on 2022-01-27 Acknowledgements: We thank the grape germplasm repositories of Consiglio per la Ricerca in agricoltura e l{\textquoteright}analisi dell{\textquoteright}Economia Agraria (CREA), Italy; Institut national de la recherche agrono-mique (INRA), Unit{\'e} Exp{\'e}rimentale du Domaine de Vassal, France; Julius Kuhn Institute, Germany; Kmetijsko Gozdarski Zavod Nova Gorica, Slovenia; and Vivai Cooperativi Rauscedo (VCR) Research Center, Italy, Italy for plant material. We also thank Goran Zduni{\'c} and Andrey Zvyagin for sharing DNA samples; Paolo Sivilotti for discussions on the variety Berzamino, Andrea Bertoli, Mara Miculan and Nicoletta Felice for DNA and RNA library preparation. This work was supported by FP7–IDEAS–ERC “Novabreed” (grant agreement no. 294780, M.M.), by the Italian Ministry of Agriculture (project Vigneto, M.M.), and by the European Regional Development Fund, Interreg Italy–Slovenia Programme 2007–2013 (grant no 081-3/2011, project VISO, G.D.G.).",

year = "2021",

month = dec,

day = "21",

doi = "10.1038/s41467-021-27487-y",

language = "English (US)",

volume = "12",

journal = "Nature communications",

issn = "2041-1723",

publisher = "Nature Research",

number = "1",

}

TY - JOUR

T1 - The genomes of 204 Vitis vinifera accessions reveal the origin of European wine grapes.

AU - Magris, Gabriele

AU - Jurman, Irena

AU - Fornasiero, Alice

AU - Paparelli, Eleonora

AU - Schwope, Rachel

AU - Marroni, Fabio

AU - Di Gaspero, Gabriele

AU - Morgante, Michele

N1 - KAUST Repository Item: Exported on 2022-01-27 Acknowledgements: We thank the grape germplasm repositories of Consiglio per la Ricerca in agricoltura e l’analisi dell’Economia Agraria (CREA), Italy; Institut national de la recherche agrono-mique (INRA), Unité Expérimentale du Domaine de Vassal, France; Julius Kuhn Institute, Germany; Kmetijsko Gozdarski Zavod Nova Gorica, Slovenia; and Vivai Cooperativi Rauscedo (VCR) Research Center, Italy, Italy for plant material. We also thank Goran Zdunić and Andrey Zvyagin for sharing DNA samples; Paolo Sivilotti for discussions on the variety Berzamino, Andrea Bertoli, Mara Miculan and Nicoletta Felice for DNA and RNA library preparation. This work was supported by FP7–IDEAS–ERC “Novabreed” (grant agreement no. 294780, M.M.), by the Italian Ministry of Agriculture (project Vigneto, M.M.), and by the European Regional Development Fund, Interreg Italy–Slovenia Programme 2007–2013 (grant no 081-3/2011, project VISO, G.D.G.).

PY - 2021/12/21

Y1 - 2021/12/21

N2 - In order to elucidate the still controversial processes that originated European wine grapes from its wild progenitor, here we analyse 204 genomes of Vitis vinifera and show that all analyses support a single domestication event that occurred in Western Asia and was followed by numerous and pervasive introgressions from European wild populations. This admixture generated the so-called international wine grapes that have diffused from Alpine countries worldwide. Across Europe, marked differences in genomic diversity are observed in local varieties that are traditionally cultivated in different wine producing countries, with Italy and France showing the largest diversity. Three genomic regions of reduced genetic diversity are observed, presumably as a consequence of artificial selection. In the lowest diversity region, two candidate genes that gained berry-specific expression in domesticated varieties may contribute to the change in berry size and morphology that makes the fruit attractive for human consumption and adapted for winemaking.

AB - In order to elucidate the still controversial processes that originated European wine grapes from its wild progenitor, here we analyse 204 genomes of Vitis vinifera and show that all analyses support a single domestication event that occurred in Western Asia and was followed by numerous and pervasive introgressions from European wild populations. This admixture generated the so-called international wine grapes that have diffused from Alpine countries worldwide. Across Europe, marked differences in genomic diversity are observed in local varieties that are traditionally cultivated in different wine producing countries, with Italy and France showing the largest diversity. Three genomic regions of reduced genetic diversity are observed, presumably as a consequence of artificial selection. In the lowest diversity region, two candidate genes that gained berry-specific expression in domesticated varieties may contribute to the change in berry size and morphology that makes the fruit attractive for human consumption and adapted for winemaking.

UR - http://hdl.handle.net/10754/675155

UR - https://www.nature.com/articles/s41467-021-27487-y

UR - http://www.scopus.com/inward/record.url?scp=85121500009&partnerID=8YFLogxK

U2 - 10.1038/s41467-021-27487-y

DO - 10.1038/s41467-021-27487-y

M3 - Article

C2 - 34934047

SN - 2041-1723

VL - 12

JO - Nature communications

JF - Nature communications

IS - 1

ER -

The genomes of 204 Vitis vinifera accessions reveal the origin of European wine grapes.

Abstract

Bibliographical note

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this