The Emerging Facets of Non-Cancerous Warburg Effect

Alyaa M. Abdel-Haleem; Nathan E. Lewis; Neema Jamshidi; Katsuhiko Mineta; Xin Gao; Takashi Gojobori

doi:10.3389/fendo.2017.00279

The Emerging Facets of Non-Cancerous Warburg Effect

Alyaa M. Abdel-Haleem, Nathan E. Lewis, Neema Jamshidi, Katsuhiko Mineta, Xin Gao, Takashi Gojobori

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64 Scopus citations

Abstract

The Warburg effect (WE), or aerobic glycolysis, is commonly recognized as a hallmark of cancer and has been extensively studied for potential anti-cancer therapeutics development. Beyond cancer, the WE plays an important role in many other cell types involved in immunity, angiogenesis, pluripotency, and infection by pathogens (e.g., malaria). Here, we review the WE in non-cancerous context as a

Original language	English (US)
Journal	Frontiers in Endocrinology
Volume	8
Issue number	OCT
DOIs	https://doi.org/10.3389/fendo.2017.00279
State	Published - Oct 23 2017

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledged KAUST grant number(s): URF/1/1976-03
Acknowledgements: AMA, XG, KM, and TG acknowledge funding from King Abdullah University of Science and Technology (KAUST) and the Office of Sponsored Research (OSR) under Award No. URF/1/1976-03. NL acknowledges generous support from the Novo Nordisk Foundation grant NNF10CC1016517 and NIH (R35-GM119850 and R01 AI090141).

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10.3389/fendo.2017.00279

https://repository.kaust.edu.sa/bitstream/10754/626124/1/fendo-08-00279.pdf

Cite this

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abstract = "The Warburg effect (WE), or aerobic glycolysis, is commonly recognized as a hallmark of cancer and has been extensively studied for potential anti-cancer therapeutics development. Beyond cancer, the WE plays an important role in many other cell types involved in immunity, angiogenesis, pluripotency, and infection by pathogens (e.g., malaria). Here, we review the WE in non-cancerous context as a",

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AU - Gao, Xin

AU - Gojobori, Takashi

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The Emerging Facets of Non-Cancerous Warburg Effect

Abstract

Bibliographical note

UN SDGs

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