Twice as good: The title reaction using the tryptophan-derived bifunctional organic catalyst 1 has been developed. The reported method led to the synthesis of chiral γ-substituted butenolides in excellent yields, with high diastereo- and enantioselectivities. Facile synthesis of chiral glycerol derivatives containing a tertiary hydroxy group has also been demonstrated. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
|Original language||English (US)|
|Number of pages||4|
|Journal||Angewandte Chemie International Edition|
|State||Published - Jan 11 2011|
Bibliographical noteKAUST Repository Item: Exported on 2020-10-01
Acknowledgements: We thank the National University of Singapore and the Ministry of Education (MOE) of Singapore (R-143-000-362-112) for generous financial support.
ASJC Scopus subject areas
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CCDC 803555: Experimental Crystal Structure Determination : (S,S)-t-Butyl (3,4-dichloro-5-oxo-2,5-dihydrofuran-2-yl)(hydroxy)2-naphthylacetate
Luo, J. (Creator), Wang, H. (Creator), Han, X. (Creator), Xu, L. (Creator), Kwiatkowski, J. (Creator), Huang, K. (Creator), Lu, Y. (Creator), Luo, J. (Creator), Wang, H. (Creator), Han, X. (Creator), Xu, L. (Creator), Kwiatkowski, J. (Creator), Lu, Y. (Creator), Luo, J. (Creator), Wang, H. (Creator), Han, X. (Creator), Xu, L. (Creator), Kwiatkowski, J. (Creator) & Lu, Y. (Creator), Cambridge Crystallographic Data Centre, 2011
DOI: 10.5517/ccvz543, http://hdl.handle.net/10754/624624