The Current Status of MOF and COF Applications

Ralph Freund, Orysia Zaremba, Giel Arnauts, Rob Ameloot, Grigorii Skorupskii, Mircea Dincă, Anastasiya Bavykina, Jorge Gascon, Aleksander Ejsmont, Joanna Gościańska, Markus Kalmutzki, Ulrich Lächelt, Evelyn Ploetz, Christian Diercks, Stefan Wuttke

Research output: Contribution to journalArticlepeer-review

468 Scopus citations


The amalgamation of different disciplines is at the heart of reticular chemistry and has broadened the boundaries of chemistry by opening up an infinite space of chemical composition, structure, and material properties. Reticular design has enabled the precise prediction of crystalline framework structures, tunability of chemical composition, incorporation of various functionalities onto the framework backbone, and as a consequence, fine-tuning of metal-organic framework (MOF) and covalent organic framework (COF) properties beyond that of any other material class. Leveraging the unique properties of reticular materials has resulted in significant advances from both a fundamental and an applied perspective. Here, we wish to review the milestones in MOF and COF research and give a critical view on progress in their real-world applications. Finally, we briefly discuss the major challenges in the field that need to be addressed to pave the way for industrial applications.
Original languageEnglish (US)
JournalAngewandte Chemie International Edition
StatePublished - May 14 2021

Bibliographical note

KAUST Repository Item: Exported on 2021-06-08
Acknowledgements: G.A. thanks the Research Foundation-Flanders (FWO) for the fellowship 1SA7320N and acknowledges Víctor Rubio-Giménez for the discussion on the conductivity of 2D MOFs.

ASJC Scopus subject areas

  • General Chemistry
  • Catalysis


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