The control of peroxisome number and size during division and proliferation

Mingda Yan, Naganand Rayapuram, Suresh Subramani*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

103 Scopus citations


Like other subcellular organelles, peroxisomes divide and segregate to daughter cells during cell division, but this organelle can also proliferate or be degraded in response to environmental cues. Although the mechanisms and genes involved in these processes are still under active investigation, an important player in peroxisome proliferation is a dynamin-related protein (DRP) that is recruited to the organelle membrane by a DRP receptor. Related DRPs also function in the division of mitochondria and chloroplasts. Many other proteins and signals regulate peroxisome division and proliferation, but their modes of action are still being studied.

Original languageEnglish (US)
Pages (from-to)376-383
Number of pages8
JournalCurrent Opinion in Cell Biology
Issue number4
StatePublished - Aug 2005
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology


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