The asparagus genome sheds light on the origin and evolution of a young y chromosome

Alex Harkess; Jinsong Zhou; Chunyan Xu; John E. Bowers; Ron Van Der Hulst; Saravanaraj Ayyampalayam; Francesco Mercati; Paolo Riccardi; Michael R. McKain; Atul Kakrana; Haibao Tang; Jeremy Ray; John Groenendijk; Siwaret Arikit; Sandra M. Mathioni; Mayumi Nakano; Hongyan Shan; Alexa Telgmann-Rauber; Akira Kanno; Zhen Yue; Haixin Chen; Wenqi Li; Yanling Chen; Xiangyang Xu; Yueping Zhang; Shaochun Luo; Helong Chen; Jianming Gao; Zichao Mao; J. Chris Pires; Meizhong Luo; Dave Kudrna; Rod A. Wing; Blake C. Meyers; Kexian Yi; Hongzhi Kong; Pierre Lavrijsen; Francesco Sunseri; Agostino Falavigna; Yin Ye; James H. Leebens-Mack; Guangyu Chen

doi:10.1038/s41467-017-01064-8

The asparagus genome sheds light on the origin and evolution of a young y chromosome

Alex Harkess, Jinsong Zhou, Chunyan Xu, John E. Bowers, Ron Van Der Hulst, Saravanaraj Ayyampalayam, Francesco Mercati, Paolo Riccardi, Michael R. McKain, Atul Kakrana, Haibao Tang, Jeremy Ray, John Groenendijk, Siwaret Arikit, Sandra M. Mathioni, Mayumi Nakano, Hongyan Shan, Alexa Telgmann-Rauber, Akira Kanno, Zhen YueHaixin Chen, Wenqi Li, Yanling Chen, Xiangyang Xu, Yueping Zhang, Shaochun Luo, Helong Chen, Jianming Gao, Zichao Mao, J. Chris Pires, Meizhong Luo, Dave Kudrna, Rod A. Wing, Blake C. Meyers, Kexian Yi, Hongzhi Kong, Pierre Lavrijsen, Francesco Sunseri, Agostino Falavigna, Yin Ye, James H. Leebens-Mack, Guangyu Chen

Research output: Contribution to journal › Article › peer-review

215 Scopus citations

Abstract

Sex chromosomes evolved from autosomes many times across the eukaryote phylogeny. Several models have been proposed to explain this transition, some involving male and female sterility mutations linked in a region of suppressed recombination between X and Y (or Z/W, U/V) chromosomes. Comparative and experimental analysis of a reference genome assembly for a double haploid YY male garden asparagus (Asparagus officinalis L.) individual implicates separate but linked genes as responsible for sex determination. Dioecy has evolved recently within Asparagus and sex chromosomes are cytogenetically identical with the Y, harboring a megabase segment that is missing from the X. We show that deletion of this entire region results in a male-to-female conversion, whereas loss of a single suppressor of female development drives male-to-hermaphrodite conversion. A single copy anther-specific gene with a male sterile Arabidopsis knockout phenotype is also in the Y-specific region, supporting a two-gene model for sex chromosome evolution.

Original language	English (US)
Journal	Nature Communications
Volume	8
Issue number	1
DOIs	https://doi.org/10.1038/s41467-017-01064-8
State	Published - Dec 1 2017
Externally published	Yes

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Generated from Scopus record by KAUST IRTS on 2019-11-20

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Harkess, A., Zhou, J., Xu, C., Bowers, J. E., Van Der Hulst, R., Ayyampalayam, S., Mercati, F., Riccardi, P., McKain, M. R., Kakrana, A., Tang, H., Ray, J., Groenendijk, J., Arikit, S., Mathioni, S. M., Nakano, M., Shan, H., Telgmann-Rauber, A., Kanno, A., ... Chen, G. (2017). The asparagus genome sheds light on the origin and evolution of a young y chromosome. Nature Communications, 8(1). https://doi.org/10.1038/s41467-017-01064-8

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title = "The asparagus genome sheds light on the origin and evolution of a young y chromosome",

abstract = "Sex chromosomes evolved from autosomes many times across the eukaryote phylogeny. Several models have been proposed to explain this transition, some involving male and female sterility mutations linked in a region of suppressed recombination between X and Y (or Z/W, U/V) chromosomes. Comparative and experimental analysis of a reference genome assembly for a double haploid YY male garden asparagus (Asparagus officinalis L.) individual implicates separate but linked genes as responsible for sex determination. Dioecy has evolved recently within Asparagus and sex chromosomes are cytogenetically identical with the Y, harboring a megabase segment that is missing from the X. We show that deletion of this entire region results in a male-to-female conversion, whereas loss of a single suppressor of female development drives male-to-hermaphrodite conversion. A single copy anther-specific gene with a male sterile Arabidopsis knockout phenotype is also in the Y-specific region, supporting a two-gene model for sex chromosome evolution.",

author = "Alex Harkess and Jinsong Zhou and Chunyan Xu and Bowers, {John E.} and {Van Der Hulst}, Ron and Saravanaraj Ayyampalayam and Francesco Mercati and Paolo Riccardi and McKain, {Michael R.} and Atul Kakrana and Haibao Tang and Jeremy Ray and John Groenendijk and Siwaret Arikit and Mathioni, {Sandra M.} and Mayumi Nakano and Hongyan Shan and Alexa Telgmann-Rauber and Akira Kanno and Zhen Yue and Haixin Chen and Wenqi Li and Yanling Chen and Xiangyang Xu and Yueping Zhang and Shaochun Luo and Helong Chen and Jianming Gao and Zichao Mao and Pires, {J. Chris} and Meizhong Luo and Dave Kudrna and Wing, {Rod A.} and Meyers, {Blake C.} and Kexian Yi and Hongzhi Kong and Pierre Lavrijsen and Francesco Sunseri and Agostino Falavigna and Yin Ye and Leebens-Mack, {James H.} and Guangyu Chen",

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Harkess, A, Zhou, J, Xu, C, Bowers, JE, Van Der Hulst, R, Ayyampalayam, S, Mercati, F, Riccardi, P, McKain, MR, Kakrana, A, Tang, H, Ray, J, Groenendijk, J, Arikit, S, Mathioni, SM, Nakano, M, Shan, H, Telgmann-Rauber, A, Kanno, A, Yue, Z, Chen, H, Li, W, Chen, Y, Xu, X, Zhang, Y, Luo, S, Chen, H, Gao, J, Mao, Z, Pires, JC, Luo, M, Kudrna, D, Wing, RA, Meyers, BC, Yi, K, Kong, H, Lavrijsen, P, Sunseri, F, Falavigna, A, Ye, Y, Leebens-Mack, JH & Chen, G 2017, 'The asparagus genome sheds light on the origin and evolution of a young y chromosome', Nature Communications, vol. 8, no. 1. https://doi.org/10.1038/s41467-017-01064-8

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AU - Zhou, Jinsong

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AU - Bowers, John E.

AU - Van Der Hulst, Ron

AU - Ayyampalayam, Saravanaraj

AU - Mercati, Francesco

AU - Riccardi, Paolo

AU - McKain, Michael R.

AU - Kakrana, Atul

AU - Tang, Haibao

AU - Ray, Jeremy

AU - Groenendijk, John

AU - Arikit, Siwaret

AU - Mathioni, Sandra M.

AU - Nakano, Mayumi

AU - Shan, Hongyan

AU - Telgmann-Rauber, Alexa

AU - Kanno, Akira

AU - Yue, Zhen

AU - Chen, Haixin

AU - Li, Wenqi

AU - Chen, Yanling

AU - Xu, Xiangyang

AU - Zhang, Yueping

AU - Luo, Shaochun

AU - Chen, Helong

AU - Gao, Jianming

AU - Mao, Zichao

AU - Pires, J. Chris

AU - Luo, Meizhong

AU - Kudrna, Dave

AU - Wing, Rod A.

AU - Meyers, Blake C.

AU - Yi, Kexian

AU - Kong, Hongzhi

AU - Lavrijsen, Pierre

AU - Sunseri, Francesco

AU - Falavigna, Agostino

AU - Ye, Yin

AU - Leebens-Mack, James H.

AU - Chen, Guangyu

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N2 - Sex chromosomes evolved from autosomes many times across the eukaryote phylogeny. Several models have been proposed to explain this transition, some involving male and female sterility mutations linked in a region of suppressed recombination between X and Y (or Z/W, U/V) chromosomes. Comparative and experimental analysis of a reference genome assembly for a double haploid YY male garden asparagus (Asparagus officinalis L.) individual implicates separate but linked genes as responsible for sex determination. Dioecy has evolved recently within Asparagus and sex chromosomes are cytogenetically identical with the Y, harboring a megabase segment that is missing from the X. We show that deletion of this entire region results in a male-to-female conversion, whereas loss of a single suppressor of female development drives male-to-hermaphrodite conversion. A single copy anther-specific gene with a male sterile Arabidopsis knockout phenotype is also in the Y-specific region, supporting a two-gene model for sex chromosome evolution.

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JO - Nature Communications

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The asparagus genome sheds light on the origin and evolution of a young y chromosome

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