Systematic multivariate optimization of supercritical fluid extraction

K. Li; C. P. Ong; S. F.Y. Li

doi:10.1093/chromsci/32.2.53

Systematic multivariate optimization of supercritical fluid extraction

K. Li^*, C. P. Ong, S. F.Y. Li

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

An interpretative method for predicting optimum conditions for supercritical fluid extraction was developed. The proposed scheme was used for the optimization of temperature, initial pressure, and pressure gradient for the extraction of vitamin E. Eleven experiments were conducted to obtain global optimum conditions. The validity of the scheme was confirmed by comparing the predicted extraction efficiencies with the experimental values. The application of the predicted optimal SFE conditions for the extraction of vitamin E in corn oil was demonstrated.

Original language	English (US)
Pages (from-to)	53-56
Number of pages	4
Journal	Journal of Chromatographic Science
Volume	32
Issue number	2
DOIs	https://doi.org/10.1093/chromsci/32.2.53
State	Published - 1994
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry

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10.1093/chromsci/32.2.53

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title = "Systematic multivariate optimization of supercritical fluid extraction",

abstract = "An interpretative method for predicting optimum conditions for supercritical fluid extraction was developed. The proposed scheme was used for the optimization of temperature, initial pressure, and pressure gradient for the extraction of vitamin E. Eleven experiments were conducted to obtain global optimum conditions. The validity of the scheme was confirmed by comparing the predicted extraction efficiencies with the experimental values. The application of the predicted optimal SFE conditions for the extraction of vitamin E in corn oil was demonstrated.",

author = "K. Li and Ong, {C. P.} and Li, {S. F.Y.}",

year = "1994",

doi = "10.1093/chromsci/32.2.53",

language = "English (US)",

volume = "32",

pages = "53--56",

journal = "Journal of Chromatographic Science",

issn = "0021-9665",

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AU - Li, K.

AU - Ong, C. P.

AU - Li, S. F.Y.

PY - 1994

Y1 - 1994

N2 - An interpretative method for predicting optimum conditions for supercritical fluid extraction was developed. The proposed scheme was used for the optimization of temperature, initial pressure, and pressure gradient for the extraction of vitamin E. Eleven experiments were conducted to obtain global optimum conditions. The validity of the scheme was confirmed by comparing the predicted extraction efficiencies with the experimental values. The application of the predicted optimal SFE conditions for the extraction of vitamin E in corn oil was demonstrated.

AB - An interpretative method for predicting optimum conditions for supercritical fluid extraction was developed. The proposed scheme was used for the optimization of temperature, initial pressure, and pressure gradient for the extraction of vitamin E. Eleven experiments were conducted to obtain global optimum conditions. The validity of the scheme was confirmed by comparing the predicted extraction efficiencies with the experimental values. The application of the predicted optimal SFE conditions for the extraction of vitamin E in corn oil was demonstrated.

UR - http://www.scopus.com/inward/record.url?scp=0028378118&partnerID=8YFLogxK

U2 - 10.1093/chromsci/32.2.53

DO - 10.1093/chromsci/32.2.53

M3 - Article

AN - SCOPUS:0028378118

SN - 0021-9665

VL - 32

SP - 53

EP - 56

JO - Journal of Chromatographic Science

JF - Journal of Chromatographic Science

IS - 2

ER -

Systematic multivariate optimization of supercritical fluid extraction

Abstract

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