Synthesis of indoles using visible light: Photoredox catalysis for palladium-catalyzed C-H activation

Jochen Zoller; David C. Fabry; Meria A. Ronge; Magnus Rueping

doi:10.1002/anie.201405478

Synthesis of indoles using visible light: Photoredox catalysis for palladium-catalyzed C-H activation

Jochen Zoller, David C. Fabry, Meria A. Ronge, Magnus Rueping^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

209 Scopus citations

Abstract

A combined palladium- and photoredox-catalyzed C-H olefination enables the synthesis of indoles. By using visible light, the direct C-H activation of aromatic enamines can be achieved and a variety of indole derivatives can be obtained in good yields under mild reaction conditions.

Original language	English (US)
Pages (from-to)	13264-13268
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	53
Issue number	48
DOIs	https://doi.org/10.1002/anie.201405478
State	Published - Nov 24 2014
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords

C-H functionalization
Heck reaction
Photocatalysis
Superoxide

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.201405478

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abstract = "A combined palladium- and photoredox-catalyzed C-H olefination enables the synthesis of indoles. By using visible light, the direct C-H activation of aromatic enamines can be achieved and a variety of indole derivatives can be obtained in good yields under mild reaction conditions.",

keywords = "C-H functionalization, Heck reaction, Photocatalysis, Superoxide",

author = "Jochen Zoller and Fabry, {David C.} and Ronge, {Meria A.} and Magnus Rueping",

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T2 - Photoredox catalysis for palladium-catalyzed C-H activation

AU - Zoller, Jochen

AU - Fabry, David C.

AU - Ronge, Meria A.

AU - Rueping, Magnus

PY - 2014/11/24

Y1 - 2014/11/24

N2 - A combined palladium- and photoredox-catalyzed C-H olefination enables the synthesis of indoles. By using visible light, the direct C-H activation of aromatic enamines can be achieved and a variety of indole derivatives can be obtained in good yields under mild reaction conditions.

AB - A combined palladium- and photoredox-catalyzed C-H olefination enables the synthesis of indoles. By using visible light, the direct C-H activation of aromatic enamines can be achieved and a variety of indole derivatives can be obtained in good yields under mild reaction conditions.

KW - C-H functionalization

KW - Heck reaction

KW - Photocatalysis

KW - Superoxide

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DO - 10.1002/anie.201405478

M3 - Article

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AN - SCOPUS:84915782332

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JF - Angewandte Chemie - International Edition

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ER -

Synthesis of indoles using visible light: Photoredox catalysis for palladium-catalyzed C-H activation

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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