Synthesis of 3-fluoro-3-aryl oxindoles: Direct enantioselective α arylation of amides

Chemistry

• N-Heterocyclic Carbene 100%
• Arylation 100%
• Ligand 100%
• Density Functional Theory 50%
• Reaction Yield 50%
• Enantioselectivity 50%
• Asymmetry 50%
• Oxindole 50%
• Synthesis (Chemical) 50%
• Chemical Reaction Product 50%
• Catalyst 50%

Chemical Engineering

• Amide 50%