Synthesis of 10β,17α-dimethyl-17β-(1,2-dioxopropyl)estra-5,9-diene-3- ketal

Valérie Gertosio; Catherine C. Santini; Jean Marie Basset; François Bayard; Michel Vivat; Jean Buendia

doi:10.1002/(SICI)1099-0690(200004)2000:8<1521::AID-EJOC1521>3.0.CO;2-F

Synthesis of 10β,17α-dimethyl-17β-(1,2-dioxopropyl)estra-5,9-diene-3- ketal

Valérie Gertosio, Catherine C. Santini^*, Jean Marie Basset, François Bayard, Michel Vivat, Jean Buendia

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The synthesis of a new progestomimetic steroid, analogous to the cetaloxopromegestone precursor of Trimegestone has been carried out in eight steps from 9α-hydroxyandrost-4-ene-3,17-dione. This latter compound can be obtained from the fermentation of γ-sitosterol, a sterol extracted from soya bean oil.

Original language	English (US)
Pages (from-to)	1521-1525
Number of pages	5
Journal	European Journal of Organic Chemistry
Issue number	8
DOIs	https://doi.org/10.1002/(SICI)1099-0690(200004)2000:8<1521::AID-EJOC1521>3.0.CO;2-F
State	Published - Apr 2000
Externally published	Yes

Keywords

Ketones
Steroids
Synthetic methods

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Organic Chemistry

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10.1002/(SICI)1099-0690(200004)2000:8<1521::AID-EJOC1521>3.0.CO;2-F

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title = "Synthesis of 10β,17α-dimethyl-17β-(1,2-dioxopropyl)estra-5,9-diene-3- ketal",

abstract = "The synthesis of a new progestomimetic steroid, analogous to the cetaloxopromegestone precursor of Trimegestone has been carried out in eight steps from 9α-hydroxyandrost-4-ene-3,17-dione. This latter compound can be obtained from the fermentation of γ-sitosterol, a sterol extracted from soya bean oil.",

keywords = "Ketones, Steroids, Synthetic methods",

author = "Val{\'e}rie Gertosio and Santini, {Catherine C.} and Basset, {Jean Marie} and Fran{\c c}ois Bayard and Michel Vivat and Jean Buendia",

year = "2000",

month = apr,

doi = "10.1002/(SICI)1099-0690(200004)2000:8<1521::AID-EJOC1521>3.0.CO;2-F",

language = "English (US)",

pages = "1521--1525",

journal = "European Journal of Organic Chemistry",

issn = "1434-193X",

number = "8",

}

TY - JOUR

T1 - Synthesis of 10β,17α-dimethyl-17β-(1,2-dioxopropyl)estra-5,9-diene-3- ketal

AU - Gertosio, Valérie

AU - Santini, Catherine C.

AU - Basset, Jean Marie

AU - Bayard, François

AU - Vivat, Michel

AU - Buendia, Jean

PY - 2000/4

Y1 - 2000/4

N2 - The synthesis of a new progestomimetic steroid, analogous to the cetaloxopromegestone precursor of Trimegestone has been carried out in eight steps from 9α-hydroxyandrost-4-ene-3,17-dione. This latter compound can be obtained from the fermentation of γ-sitosterol, a sterol extracted from soya bean oil.

AB - The synthesis of a new progestomimetic steroid, analogous to the cetaloxopromegestone precursor of Trimegestone has been carried out in eight steps from 9α-hydroxyandrost-4-ene-3,17-dione. This latter compound can be obtained from the fermentation of γ-sitosterol, a sterol extracted from soya bean oil.

KW - Ketones

KW - Steroids

KW - Synthetic methods

UR - http://www.scopus.com/inward/record.url?scp=0034017719&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1099-0690(200004)2000:8<1521::AID-EJOC1521>3.0.CO;2-F

DO - 10.1002/(SICI)1099-0690(200004)2000:8<1521::AID-EJOC1521>3.0.CO;2-F

M3 - Article

AN - SCOPUS:0034017719

SN - 1434-193X

SP - 1521

EP - 1525

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 8

ER -

Synthesis of 10β,17α-dimethyl-17β-(1,2-dioxopropyl)estra-5,9-diene-3- ketal

Abstract

Keywords

ASJC Scopus subject areas

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