Synthesis and fungicidal activity of some 8-aryl-3-(β-D-glucopyranosyl)-4-oxo-4H,5H-1,2,4-triazolo-[4,3-b]-1,4,2,6-dithiadiazine-1,1-dioxides

8-Aryl-3-(β-D-glucopyranosyl)-4-oxo-4H,5H-1,2,4-triazolo-[4,3-b]-1,4,2,6-dithiadiazine-1,1-dioxides 4 have been conveniently prepared from 8-aryl-4-oxo-4H,5H-1,2,4-triazolo-[4,3-b]-1,4,2,6-dithiadiazine-1,1-dioxides 2 by reaction of β-D-1,2,3,4,6-penta-O-acetylglucopyranose and iodine. Compounds 2 are synthesized by reported methods from 3-mercapto-5-aryl-1,2,4-triazole 1, chlorosulphonyl isocyanate and N-di-isopropyl-ethylamine in acetonitrile. All compounds have been tested in vitro for their antifungal activity against three fungal species Cephalosporium saccharii, Colletotrichum falcatum and Helminthosporium oryzae.