Synthesis and characterization of SiO2-CaO-P2O 5 hollow nanospheres for biomedical applications

G. S. Pappas; P. Bilalis; G. C. Kordas

doi:10.1016/j.matlet.2011.09.089

Synthesis and characterization of SiO₂-CaO-P₂O ₅ hollow nanospheres for biomedical applications

G. S. Pappas, P. Bilalis, G. C. Kordas^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

A ternary system of SiO₂-CaO-P₂O₅ hollow nanospheres has been successfully prepared by sol-gel method using polystyrene (PS) nanospheres as template. The inorganic shell was produced using tetraorthosilicate (TEOS) as the silica source and tri-calciumphospate as calcium and phosphorus sources, respectively. The positive surface charge of the template and the [template]/[TEOS] ratio were the key parameters for the creation of a stable primary inorganic network and the further growth of the shell. The removal of the polymeric core through a thermal treatment procedure created an inner void space with mean diameter 250 nm while the outer mean diameter was 330 nm.

Original language	English (US)
Pages (from-to)	273-276
Number of pages	4
Journal	Materials Letters
Volume	67
Issue number	1
DOIs	https://doi.org/10.1016/j.matlet.2011.09.089
State	Published - Jan 15 2012
Externally published	Yes

Bibliographical note

Funding Information:
This work was funded by the European Research Council (ERC) under the project “NANOTHERAPY” with reference number 232959.

Keywords

Bioceramics
Biomaterials
Hollow nanospheres
Sol-gel preparation

ASJC Scopus subject areas

General Materials Science
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

Access to Document

10.1016/j.matlet.2011.09.089

Cite this

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title = "Synthesis and characterization of SiO2-CaO-P2O 5 hollow nanospheres for biomedical applications",

abstract = "A ternary system of SiO2-CaO-P2O5 hollow nanospheres has been successfully prepared by sol-gel method using polystyrene (PS) nanospheres as template. The inorganic shell was produced using tetraorthosilicate (TEOS) as the silica source and tri-calciumphospate as calcium and phosphorus sources, respectively. The positive surface charge of the template and the [template]/[TEOS] ratio were the key parameters for the creation of a stable primary inorganic network and the further growth of the shell. The removal of the polymeric core through a thermal treatment procedure created an inner void space with mean diameter 250 nm while the outer mean diameter was 330 nm.",

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AU - Bilalis, P.

AU - Kordas, G. C.

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AB - A ternary system of SiO2-CaO-P2O5 hollow nanospheres has been successfully prepared by sol-gel method using polystyrene (PS) nanospheres as template. The inorganic shell was produced using tetraorthosilicate (TEOS) as the silica source and tri-calciumphospate as calcium and phosphorus sources, respectively. The positive surface charge of the template and the [template]/[TEOS] ratio were the key parameters for the creation of a stable primary inorganic network and the further growth of the shell. The removal of the polymeric core through a thermal treatment procedure created an inner void space with mean diameter 250 nm while the outer mean diameter was 330 nm.

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