Sulfination of alcohols with sodium sulfinates promoted by BF3·OEt2: An unexpected access

Mingming Huang; Liangzhen Hu; Hang Shen; Qing Liu; Muhammad Ijaz Hussain; Jing Pan; Yan Xiong

doi:10.1039/c5gc02846a

Sulfination of alcohols with sodium sulfinates promoted by BF3·OEt2: An unexpected access

Mingming Huang, Liangzhen Hu, Hang Shen, Qing Liu, Muhammad Ijaz Hussain, Jing Pan, Yan Xiong

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

A BF3·OEt2-promoted direct substitution of various alcohols with sodium sulfinates affording sulfinates under mild conditions has been developed. Further reaction of the hydroxysteroids achieves the highly complex sulfinates in good yields, which are two potential pharmacophores routinely encountered in drug discovery.

Original language	English (US)
Pages (from-to)	1874-1879
Number of pages	6
Journal	Green Chemistry
Volume	18
Issue number	7
DOIs	https://doi.org/10.1039/c5gc02846a
State	Published - Jan 1 2016
Externally published	Yes

Bibliographical note

Generated from Scopus record by KAUST IRTS on 2023-10-22

ASJC Scopus subject areas

Environmental Chemistry
Pollution

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10.1039/c5gc02846a

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abstract = "A BF3·OEt2-promoted direct substitution of various alcohols with sodium sulfinates affording sulfinates under mild conditions has been developed. Further reaction of the hydroxysteroids achieves the highly complex sulfinates in good yields, which are two potential pharmacophores routinely encountered in drug discovery.",

author = "Mingming Huang and Liangzhen Hu and Hang Shen and Qing Liu and Hussain, {Muhammad Ijaz} and Jing Pan and Yan Xiong",

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AU - Huang, Mingming

AU - Hu, Liangzhen

AU - Shen, Hang

AU - Liu, Qing

AU - Hussain, Muhammad Ijaz

AU - Pan, Jing

AU - Xiong, Yan

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PY - 2016/1/1

Y1 - 2016/1/1

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AB - A BF3·OEt2-promoted direct substitution of various alcohols with sodium sulfinates affording sulfinates under mild conditions has been developed. Further reaction of the hydroxysteroids achieves the highly complex sulfinates in good yields, which are two potential pharmacophores routinely encountered in drug discovery.

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Sulfination of alcohols with sodium sulfinates promoted by BF3·OEt2: An unexpected access

Abstract

Bibliographical note

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