Stress-related biomolecular condensates in plants.

Jorge Solis-Miranda, Monika Chodasiewicz, Aleksandra Skirycz, Alisdair R. Fernie, Panagiotis N Moschou, Peter V Bozhkov, Emilio Gutierrez-Beltran

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Biomolecular condensates are membraneless organelle-like structures that can concentrate molecules and often form through liquid-liquid phase separation. Biomolecular condensate assembly is tightly regulated by developmental and environmental cues. Although research on biomolecular condensates has intensified in the past 10 years, our current understanding of the molecular mechanisms and components underlying their formation remains in its infancy, especially in plants. However, recent studies have shown that the formation of biomolecular condensates may be central to plant acclimation to stress conditions. Here, we describe the mechanism, regulation, and properties of stress-related condensates in plants, focusing on stress granules and processing bodies, two of the most well-characterized biomolecular condensates. In this regard, we showcase the proteomes of stress granules and processing bodies, in an attempt to suggest methods for elucidating the composition and function of biomolecular condensates. Finally, we discuss how biomolecular condensates modulate stress responses and how they might be used as targets for biotechnological efforts to improve stress tolerance.
Original languageEnglish (US)
JournalThe Plant Cell
DOIs
StatePublished - May 10 2023

Bibliographical note

KAUST Repository Item: Exported on 2023-05-19
Acknowledgements: This work was supported by grants from the Ministerio de Ciencia e Innovacion, Grant PID2020- 119737GA-I00 (MCIN/AEI/10.13039/501100011033) and Junta de Andalucia (ProyExcel_00587) to EG-B, the European Union and Greek national funds through the Operational Program Competitiveness, Entrepreneurship, and Innovation, under the call RESEARCH–CREATE–INNOVATE (“BIOME” project code: Τ2ΕΔΚ-00597) to PNM, an EU Marie Curie-RISE grant (“PANTHEON”, project number 872969) to PNM, The Carl Trygger Foundation (contract number 15 and 17: 336) to PNM, The Swedish Research Council Vetenskapsrådet (VR) research council (contract number 21679000) to PNM, The Swedish FORMAS research council (contract number 22924-000) to PNM, the Hellenic Foundation of Research and Innovation (HFRI-Always Strive for Excellence-Theodoros Papazoglou, “NESTOR”, contract number 1264) to PNM, and IMBB-FORTH start-up funds to PNM; NSF 2226270 to AS, KAUST to MC and The Knut and Alice Wallenberg Foundation (contract number 2021.0071) to PVB and PNM, The Carl Trygger Foundation (contract number 22:2025) to PVB, and The Swedish Research Council VR (contract number 2019-04250) to PVB and PNM.

ASJC Scopus subject areas

  • Plant Science
  • Cell Biology

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