Stimuli responsive nanomaterials for controlled release applications

Song Li, Wengang Li, Niveen M. Khashab

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The controlled release of therapeutics has been one of the major challenges for scientists and engineers during the past three decades. Coupled with excellent biocompatibility profiles, various nanomaterials have showed great promise for biomedical applications. Stimuli-responsive nanomaterials guarantee the controlled release of cargo to a given location, at a specific time, and with an accurate amount. In this review, we have combined the major stimuli that are currently used to achieve the ultimate goal of controlled and targeted release by "smart" nanomaterials. The most heavily explored strategies include (1) pH, (2) enzymes, (3) redox, (4) magnetic, and (5) light-triggered release.
Original languageEnglish (US)
Pages (from-to)493-513
Number of pages21
JournalNanotechnology Reviews
Volume1
Issue number6
DOIs
StatePublished - Jan 1 2012

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01

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