TY - JOUR
T1 - Stimuli responsive nanomaterials for controlled release applications
AU - Li, Song
AU - Li, Wengang
AU - Khashab, Niveen M.
N1 - KAUST Repository Item: Exported on 2020-10-01
PY - 2012/1/1
Y1 - 2012/1/1
N2 - The controlled release of therapeutics has been one of the major challenges for scientists and engineers during the past three decades. Coupled with excellent biocompatibility profiles, various nanomaterials have showed great promise for biomedical applications. Stimuli-responsive nanomaterials guarantee the controlled release of cargo to a given location, at a specific time, and with an accurate amount. In this review, we have combined the major stimuli that are currently used to achieve the ultimate goal of controlled and targeted release by "smart" nanomaterials. The most heavily explored strategies include (1) pH, (2) enzymes, (3) redox, (4) magnetic, and (5) light-triggered release.
AB - The controlled release of therapeutics has been one of the major challenges for scientists and engineers during the past three decades. Coupled with excellent biocompatibility profiles, various nanomaterials have showed great promise for biomedical applications. Stimuli-responsive nanomaterials guarantee the controlled release of cargo to a given location, at a specific time, and with an accurate amount. In this review, we have combined the major stimuli that are currently used to achieve the ultimate goal of controlled and targeted release by "smart" nanomaterials. The most heavily explored strategies include (1) pH, (2) enzymes, (3) redox, (4) magnetic, and (5) light-triggered release.
UR - http://hdl.handle.net/10754/575556
UR - https://www.degruyter.com/doi/10.1515/ntrev-2012-0033
UR - http://www.scopus.com/inward/record.url?scp=84928478224&partnerID=8YFLogxK
U2 - 10.1515/ntrev-2012-0033
DO - 10.1515/ntrev-2012-0033
M3 - Article
SN - 2191-9097
VL - 1
SP - 493
EP - 513
JO - Nanotechnology Reviews
JF - Nanotechnology Reviews
IS - 6
ER -