Stem cells and interspecies chimaeras

Jun Wu, Henry T. Greely, Rudolf Jaenisch, Hiromitsu Nakauchi, Janet Rossant, Juan Carlos Izpisua Belmonte*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

134 Scopus citations

Abstract

Chimaeras are both monsters of the ancient imagination and a long-established research tool. Recent advances, particularly those dealing with the identification and generation of various kinds of stem cells, have broadened the repertoire and utility of mammalian interspecies chimaeras and carved out new paths towards understanding fundamental biology as well as potential clinical applications.

Original languageEnglish (US)
Pages (from-to)51-59
Number of pages9
JournalNATURE
Volume540
Issue number7631
DOIs
StatePublished - Dec 1 2016

Bibliographical note

Publisher Copyright:
© 2016 Macmillan Publishers Limited, part of Springer Nature.

ASJC Scopus subject areas

  • General

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