Solid phase synthesis of peptide hydroxamic acids on poly(ethylene glycol)-based support

Marta Cal; Mariusz Jaremko; Łukasz Jaremko; Piotr Stefanowicz

doi:10.1002/psc.2466

Solid phase synthesis of peptide hydroxamic acids on poly(ethylene glycol)-based support

Marta Cal, Mariusz Jaremko, Łukasz Jaremko, Piotr Stefanowicz^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A novel resin designed for solid-phase synthesis of peptide hydroxamic acids (PHA) combining the trityl linker with poly(ethylene glycol)-based support, ChemMatrix® type, is described. The synthesis of PHA can be performed according to a standard protocol, providing products in excellent purity and reasonable yields.

Original language	English (US)
Pages (from-to)	9-15
Number of pages	7
Journal	Journal of Peptide Science
Volume	19
Issue number	1
DOIs	https://doi.org/10.1002/psc.2466
State	Published - Jan 2013
Externally published	Yes

Keywords

ChemMatrix resin
Hydroxamic acid
Modified peptide
Solid phase

ASJC Scopus subject areas

Drug Discovery
Molecular Medicine
Molecular Biology
Structural Biology
Biochemistry
Pharmacology
Organic Chemistry

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10.1002/psc.2466

Cite this

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title = "Solid phase synthesis of peptide hydroxamic acids on poly(ethylene glycol)-based support",

abstract = "A novel resin designed for solid-phase synthesis of peptide hydroxamic acids (PHA) combining the trityl linker with poly(ethylene glycol)-based support, ChemMatrix{\textregistered} type, is described. The synthesis of PHA can be performed according to a standard protocol, providing products in excellent purity and reasonable yields.",

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author = "Marta Cal and Mariusz Jaremko and {\L}ukasz Jaremko and Piotr Stefanowicz",

year = "2013",

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AU - Cal, Marta

AU - Jaremko, Mariusz

AU - Jaremko, Łukasz

AU - Stefanowicz, Piotr

PY - 2013/1

Y1 - 2013/1

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AB - A novel resin designed for solid-phase synthesis of peptide hydroxamic acids (PHA) combining the trityl linker with poly(ethylene glycol)-based support, ChemMatrix® type, is described. The synthesis of PHA can be performed according to a standard protocol, providing products in excellent purity and reasonable yields.

KW - ChemMatrix resin

KW - Hydroxamic acid

KW - Modified peptide

KW - Solid phase

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M3 - Article

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ER -

Solid phase synthesis of peptide hydroxamic acids on poly(ethylene glycol)-based support

Abstract

Keywords

ASJC Scopus subject areas

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