Single-nucleotide polymorphisms in Rv2629 are specific for mycobacterium tuberculosis genotypes Beijing and Ghana but Not associated with rifampin resistance

Susanne Homolka; Claudio Köser; John Archer; Sabine Rüsch-Gerdes; Stefan Niemann

doi:10.1128/JCM.01237-08

Single-nucleotide polymorphisms in Rv2629 are specific for mycobacterium tuberculosis genotypes Beijing and Ghana but Not associated with rifampin resistance

Susanne Homolka, Claudio Köser, John Archer, Sabine Rüsch-Gerdes, Stefan Niemann^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Sequence analysis of 58 multidrug-resistant Mycobacterium tuberculosis complex strains from Germany and 55 susceptible strains from a reference collection comprising major phylogenetic lineages confirmed that variations in Rv2629, 191A/C and 965C/T, are specific for genotypes Beijing and Ghana, respectively, but not involved in the development of rifampin (rifampicin) resistance.

Original language	English (US)
Pages (from-to)	223-226
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	47
Issue number	1
DOIs	https://doi.org/10.1128/JCM.01237-08
State	Published - Jan 2009
Externally published	Yes

ASJC Scopus subject areas

Microbiology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/JCM.01237-08

Cite this

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title = "Single-nucleotide polymorphisms in Rv2629 are specific for mycobacterium tuberculosis genotypes Beijing and Ghana but Not associated with rifampin resistance",

abstract = "Sequence analysis of 58 multidrug-resistant Mycobacterium tuberculosis complex strains from Germany and 55 susceptible strains from a reference collection comprising major phylogenetic lineages confirmed that variations in Rv2629, 191A/C and 965C/T, are specific for genotypes Beijing and Ghana, respectively, but not involved in the development of rifampin (rifampicin) resistance.",

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AU - Homolka, Susanne

AU - Köser, Claudio

AU - Archer, John

AU - Rüsch-Gerdes, Sabine

AU - Niemann, Stefan

PY - 2009/1

Y1 - 2009/1

N2 - Sequence analysis of 58 multidrug-resistant Mycobacterium tuberculosis complex strains from Germany and 55 susceptible strains from a reference collection comprising major phylogenetic lineages confirmed that variations in Rv2629, 191A/C and 965C/T, are specific for genotypes Beijing and Ghana, respectively, but not involved in the development of rifampin (rifampicin) resistance.

AB - Sequence analysis of 58 multidrug-resistant Mycobacterium tuberculosis complex strains from Germany and 55 susceptible strains from a reference collection comprising major phylogenetic lineages confirmed that variations in Rv2629, 191A/C and 965C/T, are specific for genotypes Beijing and Ghana, respectively, but not involved in the development of rifampin (rifampicin) resistance.

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U2 - 10.1128/JCM.01237-08

DO - 10.1128/JCM.01237-08

M3 - Article

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SN - 0095-1137

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SP - 223

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JF - Journal of Clinical Microbiology

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Single-nucleotide polymorphisms in Rv2629 are specific for mycobacterium tuberculosis genotypes Beijing and Ghana but Not associated with rifampin resistance

Abstract

ASJC Scopus subject areas

UN SDGs

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