Short α/β-peptides as catalysts for intra- and intermolecular aldol reactions

Valerio D'Elia; Hans Zwicknagl; Oliver Reiser

doi:10.1021/jo800168h

Short α/β-peptides as catalysts for intra- and intermolecular aldol reactions

Valerio D'Elia, Hans Zwicknagl, Oliver Reiser^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

113 Scopus citations

Abstract

(Chemical Equation Presented) Short α/β-peptides, containing conformationally restricted cis-β-aminocyclopropylcarboxylic acid units as turn-inducing elements, have been found to be efficient catalysts for inter-and intramolecular aldol reactions. The tripeptide H-(L)-Pro-▲-(L)-Pro-OH was identified to perform especially well in homogeneous and heterogeneous aqueous solutions as well as in organic solvents.

Original language	English (US)
Pages (from-to)	3262-3265
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	73
Issue number	8
DOIs	https://doi.org/10.1021/jo800168h
State	Published - Apr 18 2008
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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title = "Short α/β-peptides as catalysts for intra- and intermolecular aldol reactions",

abstract = "(Chemical Equation Presented) Short α/β-peptides, containing conformationally restricted cis-β-aminocyclopropylcarboxylic acid units as turn-inducing elements, have been found to be efficient catalysts for inter-and intramolecular aldol reactions. The tripeptide H-(L)-Pro-▲-(L)-Pro-OH was identified to perform especially well in homogeneous and heterogeneous aqueous solutions as well as in organic solvents.",

author = "Valerio D'Elia and Hans Zwicknagl and Oliver Reiser",

year = "2008",

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doi = "10.1021/jo800168h",

language = "English (US)",

volume = "73",

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journal = "Journal of Organic Chemistry",

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AU - D'Elia, Valerio

AU - Zwicknagl, Hans

AU - Reiser, Oliver

PY - 2008/4/18

Y1 - 2008/4/18

N2 - (Chemical Equation Presented) Short α/β-peptides, containing conformationally restricted cis-β-aminocyclopropylcarboxylic acid units as turn-inducing elements, have been found to be efficient catalysts for inter-and intramolecular aldol reactions. The tripeptide H-(L)-Pro-▲-(L)-Pro-OH was identified to perform especially well in homogeneous and heterogeneous aqueous solutions as well as in organic solvents.

AB - (Chemical Equation Presented) Short α/β-peptides, containing conformationally restricted cis-β-aminocyclopropylcarboxylic acid units as turn-inducing elements, have been found to be efficient catalysts for inter-and intramolecular aldol reactions. The tripeptide H-(L)-Pro-▲-(L)-Pro-OH was identified to perform especially well in homogeneous and heterogeneous aqueous solutions as well as in organic solvents.

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U2 - 10.1021/jo800168h

DO - 10.1021/jo800168h

M3 - Article

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JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

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ER -

Short α/β-peptides as catalysts for intra- and intermolecular aldol reactions

Abstract

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