Sensitive and selective determination of uric acid using polyaniline and iron composite film modified electrode

Mani Govindasamy; Veerappan Mani; Shen Ming Chen; Anandaraj Sathiyan; Johnson Princy Merlin; Vinoth Kumar Ponnusamy

doi:10.20964/2016.10.63

Sensitive and selective determination of uric acid using polyaniline and iron composite film modified electrode

Mani Govindasamy, Veerappan Mani, Shen Ming Chen, Anandaraj Sathiyan, Johnson Princy Merlin, Vinoth Kumar Ponnusamy

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

We demonstrated a simple and low-cost composite composed of polyaniline and iron composite (PANI-Fe) for the determination uric acid (UA). The successful composite formation was confirmed through scanning electron microscopy, electrochemical impedance spectroscopy and electrochemical methods. The PANI-Fe composite was used to modify the surface of glassy carbon electrode (GCE) and the resulting modified electrode (PANI-Fe/GC) displayed good electrocatalytic activity to the oxidation of UA. The kinetics of the electrocatalysis and effect of scan rate were investigated. The amperometric sensor was developed based on PANI-Fe film modified electrode which delivered quick and sensitive responses to UA. The linear range is 0.05-3860 μM, detection limit is 21.5 nM, and sensitivity is 0.2981 μAμM-1 cm-2. The electrode is highly selective for UA detection. Besides, the electrode has good repeatability and reproducibility. The real-time applicability is verified in human urine samples which displayed recoveries in acceptable range.

Original language	English (US)
Pages (from-to)	8730-8737
Number of pages	8
Journal	International Journal of Electrochemical Science
Volume	11
Issue number	10
DOIs	https://doi.org/10.20964/2016.10.63
State	Published - Jan 1 2016
Externally published	Yes

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Generated from Scopus record by KAUST IRTS on 2023-09-21

ASJC Scopus subject areas

Electrochemistry

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title = "Sensitive and selective determination of uric acid using polyaniline and iron composite film modified electrode",

abstract = "We demonstrated a simple and low-cost composite composed of polyaniline and iron composite (PANI-Fe) for the determination uric acid (UA). The successful composite formation was confirmed through scanning electron microscopy, electrochemical impedance spectroscopy and electrochemical methods. The PANI-Fe composite was used to modify the surface of glassy carbon electrode (GCE) and the resulting modified electrode (PANI-Fe/GC) displayed good electrocatalytic activity to the oxidation of UA. The kinetics of the electrocatalysis and effect of scan rate were investigated. The amperometric sensor was developed based on PANI-Fe film modified electrode which delivered quick and sensitive responses to UA. The linear range is 0.05-3860 μM, detection limit is 21.5 nM, and sensitivity is 0.2981 μAμM-1 cm-2. The electrode is highly selective for UA detection. Besides, the electrode has good repeatability and reproducibility. The real-time applicability is verified in human urine samples which displayed recoveries in acceptable range.",

author = "Mani Govindasamy and Veerappan Mani and Chen, {Shen Ming} and Anandaraj Sathiyan and Merlin, {Johnson Princy} and Ponnusamy, {Vinoth Kumar}",

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T1 - Sensitive and selective determination of uric acid using polyaniline and iron composite film modified electrode

AU - Govindasamy, Mani

AU - Mani, Veerappan

AU - Chen, Shen Ming

AU - Sathiyan, Anandaraj

AU - Merlin, Johnson Princy

AU - Ponnusamy, Vinoth Kumar

N1 - Generated from Scopus record by KAUST IRTS on 2023-09-21

PY - 2016/1/1

Y1 - 2016/1/1

N2 - We demonstrated a simple and low-cost composite composed of polyaniline and iron composite (PANI-Fe) for the determination uric acid (UA). The successful composite formation was confirmed through scanning electron microscopy, electrochemical impedance spectroscopy and electrochemical methods. The PANI-Fe composite was used to modify the surface of glassy carbon electrode (GCE) and the resulting modified electrode (PANI-Fe/GC) displayed good electrocatalytic activity to the oxidation of UA. The kinetics of the electrocatalysis and effect of scan rate were investigated. The amperometric sensor was developed based on PANI-Fe film modified electrode which delivered quick and sensitive responses to UA. The linear range is 0.05-3860 μM, detection limit is 21.5 nM, and sensitivity is 0.2981 μAμM-1 cm-2. The electrode is highly selective for UA detection. Besides, the electrode has good repeatability and reproducibility. The real-time applicability is verified in human urine samples which displayed recoveries in acceptable range.

AB - We demonstrated a simple and low-cost composite composed of polyaniline and iron composite (PANI-Fe) for the determination uric acid (UA). The successful composite formation was confirmed through scanning electron microscopy, electrochemical impedance spectroscopy and electrochemical methods. The PANI-Fe composite was used to modify the surface of glassy carbon electrode (GCE) and the resulting modified electrode (PANI-Fe/GC) displayed good electrocatalytic activity to the oxidation of UA. The kinetics of the electrocatalysis and effect of scan rate were investigated. The amperometric sensor was developed based on PANI-Fe film modified electrode which delivered quick and sensitive responses to UA. The linear range is 0.05-3860 μM, detection limit is 21.5 nM, and sensitivity is 0.2981 μAμM-1 cm-2. The electrode is highly selective for UA detection. Besides, the electrode has good repeatability and reproducibility. The real-time applicability is verified in human urine samples which displayed recoveries in acceptable range.

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DO - 10.20964/2016.10.63

M3 - Article

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VL - 11

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EP - 8737

JO - International Journal of Electrochemical Science

JF - International Journal of Electrochemical Science

IS - 10

ER -

Sensitive and selective determination of uric acid using polyaniline and iron composite film modified electrode

Abstract

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