Self-assembling tetrameric peptides allowin situ3D bioprinting under physiological conditions

Sakandar Rauf; Hepi H. Susapto; Kowther Kahin; Salwa Alshehri; Sherin Abdelrahman; Jordy Homing Lam; Sultan Asad; Sandip Jadhav; Dhakshinamoorthy Sundaramurthi; Xin Gao; Charlotte A.E. Hauser

doi:10.1039/d0tb02424d

Self-assembling tetrameric peptides allowin situ3D bioprinting under physiological conditions

Sakandar Rauf, Hepi H. Susapto, Kowther Kahin, Salwa Alshehri, Sherin Abdelrahman, Jordy Homing Lam, Sultan Asad, Sandip Jadhav, Dhakshinamoorthy Sundaramurthi, Xin Gao, Charlotte A.E. Hauser^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

We have developed anin situbioprinting method that allows the printing of cells under true physiological conditions by applying self-assembling ultrashort peptides as bioinks. This method avoids cell stressing methods, such as UV-treatment, chemical crosslinking and viscous bioink printing methods. We further demonstrate that different nanomaterials can easily be synthesized or incorporated in the 3D bioprinted peptide scaffolds which opens up the possibility of functionalized 3D scaffolds.

Original language	English (US)
Pages (from-to)	1069-1081
Number of pages	13
Journal	Journal of Materials Chemistry B
Volume	9
Issue number	4
DOIs	https://doi.org/10.1039/d0tb02424d
State	Published - Jan 28 2021

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2021.

ASJC Scopus subject areas

General Chemistry
Biomedical Engineering
General Materials Science

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10.1039/d0tb02424d

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title = "Self-assembling tetrameric peptides allowin situ3D bioprinting under physiological conditions",

abstract = "We have developed anin situbioprinting method that allows the printing of cells under true physiological conditions by applying self-assembling ultrashort peptides as bioinks. This method avoids cell stressing methods, such as UV-treatment, chemical crosslinking and viscous bioink printing methods. We further demonstrate that different nanomaterials can easily be synthesized or incorporated in the 3D bioprinted peptide scaffolds which opens up the possibility of functionalized 3D scaffolds.",

author = "Sakandar Rauf and Susapto, {Hepi H.} and Kowther Kahin and Salwa Alshehri and Sherin Abdelrahman and Lam, {Jordy Homing} and Sultan Asad and Sandip Jadhav and Dhakshinamoorthy Sundaramurthi and Xin Gao and Hauser, {Charlotte A.E.}",

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doi = "10.1039/d0tb02424d",

language = "English (US)",

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T1 - Self-assembling tetrameric peptides allowin situ3D bioprinting under physiological conditions

AU - Rauf, Sakandar

AU - Susapto, Hepi H.

AU - Kahin, Kowther

AU - Alshehri, Salwa

AU - Abdelrahman, Sherin

AU - Lam, Jordy Homing

AU - Asad, Sultan

AU - Jadhav, Sandip

AU - Sundaramurthi, Dhakshinamoorthy

AU - Gao, Xin

AU - Hauser, Charlotte A.E.

PY - 2021/1/28

Y1 - 2021/1/28

N2 - We have developed anin situbioprinting method that allows the printing of cells under true physiological conditions by applying self-assembling ultrashort peptides as bioinks. This method avoids cell stressing methods, such as UV-treatment, chemical crosslinking and viscous bioink printing methods. We further demonstrate that different nanomaterials can easily be synthesized or incorporated in the 3D bioprinted peptide scaffolds which opens up the possibility of functionalized 3D scaffolds.

AB - We have developed anin situbioprinting method that allows the printing of cells under true physiological conditions by applying self-assembling ultrashort peptides as bioinks. This method avoids cell stressing methods, such as UV-treatment, chemical crosslinking and viscous bioink printing methods. We further demonstrate that different nanomaterials can easily be synthesized or incorporated in the 3D bioprinted peptide scaffolds which opens up the possibility of functionalized 3D scaffolds.

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U2 - 10.1039/d0tb02424d

DO - 10.1039/d0tb02424d

M3 - Article

C2 - 33406193

AN - SCOPUS:85100462535

SN - 2050-750X

VL - 9

SP - 1069

EP - 1081

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

IS - 4

ER -

Self-assembling tetrameric peptides allowin situ3D bioprinting under physiological conditions

Abstract

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