Self-assembling tetrameric peptides allowin situ3D bioprinting under physiological conditions

Sakandar Rauf, Hepi H. Susapto, Kowther Kahin, Salwa Alshehri, Sherin Abdelrahman, Jordy Homing Lam, Sultan Asad, Sandip Jadhav, Dhakshinamoorthy Sundaramurthi, Xin Gao, Charlotte A.E. Hauser*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

We have developed anin situbioprinting method that allows the printing of cells under true physiological conditions by applying self-assembling ultrashort peptides as bioinks. This method avoids cell stressing methods, such as UV-treatment, chemical crosslinking and viscous bioink printing methods. We further demonstrate that different nanomaterials can easily be synthesized or incorporated in the 3D bioprinted peptide scaffolds which opens up the possibility of functionalized 3D scaffolds.

Original languageEnglish (US)
Pages (from-to)1069-1081
Number of pages13
JournalJournal of Materials Chemistry B
Volume9
Issue number4
DOIs
StatePublished - Jan 28 2021

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2021.

ASJC Scopus subject areas

  • General Chemistry
  • Biomedical Engineering
  • General Materials Science

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