An efficient room temperature copper-catalyzed trifluoromethylation of organotrifluoroborates under the base free condition using an electrophilic trifluoromethylating reagent is demonstrated. The corresponding trifluoromethylarenes were obtained in good to excellent yields and the reaction tolerates a wide range of functional groups. © 2012 Elsevier Ltd. All rights reserved.
|Original language||English (US)|
|Number of pages||5|
|State||Published - Dec 2012|
Bibliographical noteKAUST Repository Item: Exported on 2020-10-01
Acknowledgements: We acknowledge the financial support from National Natural Science Foundation of China (21072030) and Fuzhou University (022318) to Z.W. and King Abdullah University of Science and Technology to K.-W.H.
ASJC Scopus subject areas
- Organic Chemistry
- Drug Discovery