Role of tissue structure in photon migration through breast tissues

Frédéric Bevilacqua, Pierre Marquet, Olivier Coquoz, Christian Depeursinge

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Photon migration has been investigated experimentally in vitro on human breast tissues, bovine liver, tissue phantoms, and theoretically by Monte Carlo simulations and diffusion theory. The spatial intensity profiles have been measured at the output surface of a sample illuminated by a collimated beam. Experimental results have then been compared with simulations that assume the sample to be homogeneous. Measurements on phantoms, i.e., fat emulsion and microspheres suspension, and on liver are in good agreement with theory. On the other hand, the width of the intensity profiles measured on breast tissues (adipose and fibrous) are systematically larger than those measured on phantoms or calculated by simulations. The structure of these samples, not considered in simulations and not present in phantoms, explains these differences.

Original languageEnglish (US)
Pages (from-to)44-51
Number of pages8
JournalApplied Optics
Issue number1
StatePublished - Jan 1 1997
Externally publishedYes


  • Heterogeneity
  • Monte Carlo
  • Photon migration
  • Scattering
  • Tissue

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Engineering (miscellaneous)
  • Electrical and Electronic Engineering


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