Removal of suspended particles from extract of tuna spleen by microfiltration: Experimental evaluation of a low fouling condition

Zhenyu Li, Wirote Youravong, Aran H-Kittikun*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


A batch concentration microfiltration with a hollow fiber membrane (pore size of 0.10 μm) was successfully employed as a pretreatment process to remove suspended particles from extract of yellowfin tuna spleen before recovery of proteases by ultafiltration. It was found that all visible suspended particles and more than half amount of soluble proteins were rejected. The transmission was about 0.8 and 0.6 for trypsin and chymotrypsin, respectively. A clear permeate with slightly yellow colour was obtained. Based on critical ratio of permeate flux (J) to wall shear stress (τw), the condition for sustainable operation with low fouling was experimentally evaluated. An empirical model of relation between critical J/τw and volume concentration factor (VCF) was found as J/τw = 3.29(VCF)-0.74 at a given transmembrane pressure of 0.15 bar. The equation indicated a condition, below which there is no marked fouling and above which sharp increase of fouling could occur. The present study revealed a simple method to predict low fouling condition in batch concentration operation during membrane separation process.

Original languageEnglish (US)
Pages (from-to)309-315
Number of pages7
JournalJournal of Food Engineering
Issue number2
StatePublished - Mar 1 2008


  • Batch concentration
  • Microfiltration
  • Modeling
  • Proteases
  • Suspended particles
  • Tuna spleen

ASJC Scopus subject areas

  • Food Science

Cite this