Receptor kinase module targets PIN-dependent auxin transport during canalization

Jakub Hajný, Tomáš Prát, Nikola Rydza, Lesia Rodriguez, Shutang Tan, Inge Verstraeten, David Domjan, Ewa Mazur, Elwira Smakowska-Luzan, Wouter Smet, Eliana Mor, Jonah Nolf, Bao Jun Yang, Wim Grunewald, Gergely Molnár, Youssef Belkhadir, Bert De Rybel, Jiří Friml

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

Spontaneously arising channels that transport the phytohormone auxin provide positional cues for selforganizing aspects of plant development such as flexible vasculature regeneration or its patterning during leaf venation. The auxin canalization hypothesis proposes a feedback between auxin signaling and transport as the underlying mechanism, but molecular players await discovery. We identified part of the machinery that routes auxin transport. The auxin-regulated receptor CAMEL (Canalization-related Auxin-regulated Malectin-type RLK) together with CANAR (Canalization-related Receptor-like kinase) interact with and phosphorylate PIN auxin transporters. camel and canar mutants are impaired in PIN1 subcellular trafficking and auxin-mediated PIN polarization, which macroscopically manifests as defects in leaf venation and vasculature regeneration after wounding. The CAMEL-CANAR receptor complex is part of the auxin feedback that coordinates polarization of individual cells during auxin canalization.
Original languageEnglish (US)
Pages (from-to)550-557
Number of pages8
JournalSCIENCE
Volume370
Issue number6516
DOIs
StatePublished - Oct 30 2020

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Generated from Scopus record by KAUST IRTS on 2023-10-23

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