Recent advances in nanosuspension technology for drug delivery

Daisy Arora, Bharat Khurana, Goutam Rath, Sanju Nanda, Amit K. Goyal

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Background: Discovery and development of BCS class 1 drugs through high throughput screening is one of the biggest challenge faced by formulation scientist. Methods: There are a number of approaches that have been exploited to enhance the solubility and permeability of drugs. Among them, development of nanosuspension has offered several benefits. These techniques may increase effective surface area due to nanonization of drug particles and further increases saturation solubility and dissolution properties for improved bioavailability. Various development methods are patented which are cost effective and easy to scale up. Conclusion: Several unique features of nanosuspension make it a versatile delivery system for different routes of administration including oral, dermal, ocular, parenteral and pulmonary. The present review is focused on preparatory techniques and formulation considerations of nanosuspension. Brief information about evaluation parameters, applications of nanosuspension in drug delivery and patented and marketed products available is also discussed.
Original languageEnglish (US)
Pages (from-to)2403-2415
Number of pages13
JournalCurrent Pharmaceutical Design
Volume24
Issue number21
DOIs
StatePublished - Jan 1 2018
Externally publishedYes

Bibliographical note

Generated from Scopus record by KAUST IRTS on 2023-10-12

Fingerprint

Dive into the research topics of 'Recent advances in nanosuspension technology for drug delivery'. Together they form a unique fingerprint.

Cite this