Recent advances in metal nanoparticles in cancer therapy

Ankush Sharma, Amit K. Goyal, Goutam Rath

Research output: Contribution to journalArticlepeer-review

245 Scopus citations

Abstract

Metal nanoparticles (NPs) may have the potential to overcome problems related to conventional chemotherapy. Metal NPs reported to play a beneficial and powerful role in cancer therapy providing better targeting, gene silencing and drug delivery. Functionalised metal NPs with targeting ligands offer a better control of energy deposition in the tumours. Apart from therapeutic benefits, metal NPs are also used as a diagnostic tool for the imaging of cancer cells. Metal NP-based therapeutic systems not only provide simultaneous diagnostic and therapy but also allow controlled and targeted drug release which helps to revolutionise cancer treatment and management. This review addresses the advancement of metal NPs in tumour therapy with a focus on those being explained into clinical settings.
Original languageEnglish (US)
Pages (from-to)617-632
Number of pages16
JournalJournal of Drug Targeting
Volume26
Issue number8
DOIs
StatePublished - Sep 14 2018
Externally publishedYes

Bibliographical note

Generated from Scopus record by KAUST IRTS on 2023-10-12

ASJC Scopus subject areas

  • Pharmaceutical Science

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