Rational design of Au nanorods assemblies for highly sensitive and selective SERS detection of prostate specific antigen

An Qi Yang; Dong Wang; Xiang Wang; Yu Han; Xue Bin Ke; Hong Jun Wang; Xi Zhou; Lei Ren

doi:10.1039/c5ra01322d

Rational design of Au nanorods assemblies for highly sensitive and selective SERS detection of prostate specific antigen

An Qi Yang, Dong Wang, Xiang Wang, Yu Han, Xue Bin Ke, Hong Jun Wang, Xi Zhou^*, Lei Ren

^*Corresponding author for this work

Physical Sciences and Engineering

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

A versatile approach for highly sensitive surface-enhanced Raman scattering (SERS) detection of prostate specific antigen (PSA) has been developed based on immune recognition assisted fabrication of gold nanorods (AuNRs) assemblies. Compared with the typical enzyme-linked immunosorbent assay, this SERS immunoassay strategy showed an obviously enhanced sensitivity. The SERS immunoassay for PSA detection has also been successfully applied in diluted human serum samples, showing the promising potential for early diagnosis of diseases in clinical application.

Original language	English (US)
Pages (from-to)	38354-38360
Number of pages	7
Journal	RSC ADVANCES
Volume	5
Issue number	48
DOIs	https://doi.org/10.1039/c5ra01322d
State	Published - 2015

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2015.

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/c5ra01322d

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abstract = "A versatile approach for highly sensitive surface-enhanced Raman scattering (SERS) detection of prostate specific antigen (PSA) has been developed based on immune recognition assisted fabrication of gold nanorods (AuNRs) assemblies. Compared with the typical enzyme-linked immunosorbent assay, this SERS immunoassay strategy showed an obviously enhanced sensitivity. The SERS immunoassay for PSA detection has also been successfully applied in diluted human serum samples, showing the promising potential for early diagnosis of diseases in clinical application.",

author = "Yang, {An Qi} and Dong Wang and Xiang Wang and Yu Han and Ke, {Xue Bin} and Wang, {Hong Jun} and Xi Zhou and Lei Ren",

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AU - Yang, An Qi

AU - Wang, Dong

AU - Wang, Xiang

AU - Han, Yu

AU - Ke, Xue Bin

AU - Wang, Hong Jun

AU - Zhou, Xi

AU - Ren, Lei

PY - 2015

Y1 - 2015

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AB - A versatile approach for highly sensitive surface-enhanced Raman scattering (SERS) detection of prostate specific antigen (PSA) has been developed based on immune recognition assisted fabrication of gold nanorods (AuNRs) assemblies. Compared with the typical enzyme-linked immunosorbent assay, this SERS immunoassay strategy showed an obviously enhanced sensitivity. The SERS immunoassay for PSA detection has also been successfully applied in diluted human serum samples, showing the promising potential for early diagnosis of diseases in clinical application.

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ER -

Rational design of Au nanorods assemblies for highly sensitive and selective SERS detection of prostate specific antigen

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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