Racemic alcohols to optically pure amine precursors enabled by catalyst dynamic kinetic resolution: experiment and computation

Luis Miguel Azofra, Mai Anh Tran, Viktoriia Zubar, Luigi Cavallo, Magnus Rueping, Osama El-Sepelgy

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

An unprecedented base metal catalysed asymmetric synthesis of α-chiral amine precursors from racemic alcohols is reported. This redox-neutral reaction utilises a bench-stable manganese complex and Ellman’s sulfinamide as versatile ammonia...
Original languageEnglish (US)
JournalChemical Communications
DOIs
StatePublished - Jun 29 2020

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: L.M.A thank Universidad de Las Palmas de Gran Canaria (ULPGC) for support. Gratitude is also due to the KAUST for using the supercomputer Shaheen II for providing the computational resources.

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