TY - JOUR
T1 - R we there yet? Advances in cloning resistance genes for engineering immunity in crop plants
AU - Chen, Renjie
AU - Gajendiran, Karthick
AU - Wulff, Brande B.H.
N1 - Publisher Copyright:
© 2023 The Authors
PY - 2024/2
Y1 - 2024/2
N2 - Over the past three decades, significant progress has been made in the field of resistance (R) gene cloning. Advances in recombinant DNA technology, genome sequencing, bioinformatics, plant transformation and plant husbandry have facilitated the transition from cloning R genes in model species to crop plants and their wild relatives. To date, researchers have isolated more than 450 R genes that play important roles in plant immunity. The molecular and biochemical mechanisms by which intracellular immune receptors are activated and initiate defense responses are now well understood. These advances present exciting opportunities for engineering disease-resistant crop plants that are protected by genetics rather than pesticides.
AB - Over the past three decades, significant progress has been made in the field of resistance (R) gene cloning. Advances in recombinant DNA technology, genome sequencing, bioinformatics, plant transformation and plant husbandry have facilitated the transition from cloning R genes in model species to crop plants and their wild relatives. To date, researchers have isolated more than 450 R genes that play important roles in plant immunity. The molecular and biochemical mechanisms by which intracellular immune receptors are activated and initiate defense responses are now well understood. These advances present exciting opportunities for engineering disease-resistant crop plants that are protected by genetics rather than pesticides.
UR - http://www.scopus.com/inward/record.url?scp=85180579105&partnerID=8YFLogxK
U2 - 10.1016/j.pbi.2023.102489
DO - 10.1016/j.pbi.2023.102489
M3 - Review article
C2 - 38128298
AN - SCOPUS:85180579105
SN - 1369-5266
VL - 77
JO - Current Opinion in Plant Biology
JF - Current Opinion in Plant Biology
M1 - 102489
ER -