Proteome-Wide Chromatin Interactomics to Study Plant Epigenetics.

Yanmei Chen; Peng Liu

doi:10.1016/j.tplants.2021.04.002

Proteome-Wide Chromatin Interactomics to Study Plant Epigenetics.

Yanmei Chen, Peng Liu

King Abdullah University of Science and Technology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Over 1000 proteins interact with and regulate plant chromatin, but the functions of most of these proteins are unclear. Advances in quantitative mass spectrometry (MS), interactomic mapping, and machine learning applications for data analysis have enabled proteome-wide investigations of chromatin regulation and in vivo studies of chromatin-bound protein functions and complex formation. Characterizing the protein-centric chromatin interactome would provide clues to how chromatin regulates epigenome landscapes and transcriptional programs related to diverse environmental and developmental cues.

Original language	English (US)
Journal	Trends in plant science
DOIs	https://doi.org/10.1016/j.tplants.2021.04.002
State	Published - May 12 2021

Bibliographical note

KAUST Repository Item: Exported on 2021-06-10
Acknowledgements: The work was supported by grants from National Natural Science Foundation of China (31470345 to Y.C.). The authors have no interests to declare.

ASJC Scopus subject areas

Plant Science

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10.1016/j.tplants.2021.04.002

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title = "Proteome-Wide Chromatin Interactomics to Study Plant Epigenetics.",

abstract = "Over 1000 proteins interact with and regulate plant chromatin, but the functions of most of these proteins are unclear. Advances in quantitative mass spectrometry (MS), interactomic mapping, and machine learning applications for data analysis have enabled proteome-wide investigations of chromatin regulation and in vivo studies of chromatin-bound protein functions and complex formation. Characterizing the protein-centric chromatin interactome would provide clues to how chromatin regulates epigenome landscapes and transcriptional programs related to diverse environmental and developmental cues.",

author = "Yanmei Chen and Peng Liu",

note = "KAUST Repository Item: Exported on 2021-06-10 Acknowledgements: The work was supported by grants from National Natural Science Foundation of China (31470345 to Y.C.). The authors have no interests to declare.",

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doi = "10.1016/j.tplants.2021.04.002",

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AU - Liu, Peng

N1 - KAUST Repository Item: Exported on 2021-06-10 Acknowledgements: The work was supported by grants from National Natural Science Foundation of China (31470345 to Y.C.). The authors have no interests to declare.

PY - 2021/5/12

Y1 - 2021/5/12

N2 - Over 1000 proteins interact with and regulate plant chromatin, but the functions of most of these proteins are unclear. Advances in quantitative mass spectrometry (MS), interactomic mapping, and machine learning applications for data analysis have enabled proteome-wide investigations of chromatin regulation and in vivo studies of chromatin-bound protein functions and complex formation. Characterizing the protein-centric chromatin interactome would provide clues to how chromatin regulates epigenome landscapes and transcriptional programs related to diverse environmental and developmental cues.

AB - Over 1000 proteins interact with and regulate plant chromatin, but the functions of most of these proteins are unclear. Advances in quantitative mass spectrometry (MS), interactomic mapping, and machine learning applications for data analysis have enabled proteome-wide investigations of chromatin regulation and in vivo studies of chromatin-bound protein functions and complex formation. Characterizing the protein-centric chromatin interactome would provide clues to how chromatin regulates epigenome landscapes and transcriptional programs related to diverse environmental and developmental cues.

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UR - https://linkinghub.elsevier.com/retrieve/pii/S1360138521000935

UR - http://www.scopus.com/inward/record.url?scp=85105518540&partnerID=8YFLogxK

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SN - 1360-1385

JO - Trends in Plant Science

JF - Trends in Plant Science

ER -

Proteome-Wide Chromatin Interactomics to Study Plant Epigenetics.

Abstract

Bibliographical note

ASJC Scopus subject areas

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