Process Intensification via Continuous and Simultaneous Isolation of Antioxidants: An Upcycling Approach for Olive Leaf Waste

Virag Voros, Enrico Drioli, Claudio Fonte, Gyorgy Szekely

Research output: Contribution to journalArticlepeer-review

55 Scopus citations

Abstract

The isolation of individual pharmaceutical-grade bioactive compounds from complex plant extracts is still a sustainability challenge. Process intensification improves manufacturing design to achieve significant benefits in process efficiency and operation, product quality, and waste management. A process optimization and intensification methodology for the simultaneous isolation of biophenols from agricultural waste, using imprinted materials and nanofiltration membranes, is reported herein. First, temperature-swing molecular imprinting technology was used to selectively extract individual biophenols from olive leaf extracts. Second, solvent-resistant nanofiltration was used to
Original languageEnglish (US)
Pages (from-to)18444-18452
Number of pages9
JournalACS Sustainable Chemistry and Engineering
Volume7
Issue number22
DOIs
StatePublished - Oct 4 2019

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: The useful discussions provided by Levente Cseri and the preliminary results obtained by Dr Christos Didaskalou, both from The University of Manchester, are greatly acknowledged. The TOC illustration was produced by Xavier Pita, scientific illustrator at King Abdullah University of Science and Technology (KAUST). This work was supported by the Royal Academy of Engineering’s Newton Research Collaboration Programme [NRCP1516/1/41].

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