Process Intensification via Continuous and Simultaneous Isolation of Antioxidants: An Upcycling Approach for Olive Leaf Waste

Virag Voros; Enrico Drioli; Claudio Fonte; Gyorgy Szekely

doi:10.1021/acssuschemeng.9b04245

Process Intensification via Continuous and Simultaneous Isolation of Antioxidants: An Upcycling Approach for Olive Leaf Waste

Virag Voros, Enrico Drioli, Claudio Fonte, Gyorgy Szekely

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

The isolation of individual pharmaceutical-grade bioactive compounds from complex plant extracts is still a sustainability challenge. Process intensification improves manufacturing design to achieve significant benefits in process efficiency and operation, product quality, and waste management. A process optimization and intensification methodology for the simultaneous isolation of biophenols from agricultural waste, using imprinted materials and nanofiltration membranes, is reported herein. First, temperature-swing molecular imprinting technology was used to selectively extract individual biophenols from olive leaf extracts. Second, solvent-resistant nanofiltration was used to

Original language	English (US)
Pages (from-to)	18444-18452
Number of pages	9
Journal	ACS Sustainable Chemistry and Engineering
Volume	7
Issue number	22
DOIs	https://doi.org/10.1021/acssuschemeng.9b04245
State	Published - Oct 4 2019

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: The useful discussions provided by Levente Cseri and the preliminary results obtained by Dr Christos Didaskalou, both from The University of Manchester, are greatly acknowledged. The TOC illustration was produced by Xavier Pita, scientific illustrator at King Abdullah University of Science and Technology (KAUST). This work was supported by the Royal Academy of Engineering’s Newton Research Collaboration Programme [NRCP1516/1/41].

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10.1021/acssuschemeng.9b04245

https://repository.kaust.edu.sa/bitstream/10754/659496/1/Revised%20Manuscript.pdf

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title = "Process Intensification via Continuous and Simultaneous Isolation of Antioxidants: An Upcycling Approach for Olive Leaf Waste",

abstract = "The isolation of individual pharmaceutical-grade bioactive compounds from complex plant extracts is still a sustainability challenge. Process intensification improves manufacturing design to achieve significant benefits in process efficiency and operation, product quality, and waste management. A process optimization and intensification methodology for the simultaneous isolation of biophenols from agricultural waste, using imprinted materials and nanofiltration membranes, is reported herein. First, temperature-swing molecular imprinting technology was used to selectively extract individual biophenols from olive leaf extracts. Second, solvent-resistant nanofiltration was used to",

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AU - Drioli, Enrico

AU - Fonte, Claudio

AU - Szekely, Gyorgy

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: The useful discussions provided by Levente Cseri and the preliminary results obtained by Dr Christos Didaskalou, both from The University of Manchester, are greatly acknowledged. The TOC illustration was produced by Xavier Pita, scientific illustrator at King Abdullah University of Science and Technology (KAUST). This work was supported by the Royal Academy of Engineering’s Newton Research Collaboration Programme [NRCP1516/1/41].

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Process Intensification via Continuous and Simultaneous Isolation of Antioxidants: An Upcycling Approach for Olive Leaf Waste

Abstract

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