TY - JOUR
T1 - Prevalence of anti-SARS-CoV-2 antibody in hemodialysis facilities: a cross-sectional multicenter study from Madinah
AU - Housawi, Abdulrahman A.
AU - Qazi, Shazada Junaid S.
AU - Jan, Abdulhalem A.
AU - Osman, Rashid A.
AU - Alshamrani, Mashil M.
AU - AlFaadhel, Talal A.
AU - AlHejaili, Fayez F.
AU - Al-Tawfiq, Jaffar A.
AU - Wafa, Ahmed A.
AU - Hamza, Abdulmageed E.
AU - Hassan, Moustafa A.
AU - Alharbi, Suliman A.
AU - Albasheer, Hamza
AU - Almohmmdi, Majed M.
AU - Alsisi, Salem A.
AU - Mankowski, Michal
AU - van de Klundert, Joris
AU - Alhelal, Amal M.
AU - Sala, Fatima H.
AU - Kheyami, Ali
AU - Alhomayeed, Bader A.
N1 - KAUST Repository Item: Exported on 2022-09-14
Acknowledgements: The authors would like to extend their gratitude to the Assistant Minister Of Health Dr. Mohammed Al-Abdulaali and the General Supervisor of Laboratory Services and Blood Transfusion at the Ministry of Health Dr. Maram Alotaibi for their great support.
PY - 2022/8/4
Y1 - 2022/8/4
N2 - BACKGROUND: Since the occurrence of coronavirus disease in 2019 (COVID-19), the global community has witnessed its exponential spread with devastating outcomes within the general population and specifically within hemodialysis patients.
OBJECTIVES: Compare the state of immunity to SARS-CoV-2 among hemodialysis patients and staff.
DESIGN: Cross-sectional study with a prospective follow-up period.
SETTING: Hemodialysis centers in Madinah region.
PATIENTS AND METHODS: We prospectively tested for SARS-CoV-2 antibodies in dialysis patients using dialysis centers staff as controls. The participants were tested on four occasions when feasible for the presence of anti-SARS-CoV-2 antibodies. We also analyzed factors that might be associated with seropositivity.
MAIN OUTCOME MEASURES: SARS-CoV-2 positivity using immunoglobulin G (IgG) levels
SAMPLE SIZE: 830 participants, 677 patients and 153 dialysis centers staff as controls.
RESULTS: Of the total participants, 325 (257 patients and 68 staff) were positive for SARS-CoV-2 IgG antibodies, for a prevalence of 38.0% and 44.4% among patients and staff, respectively (P=.1379). Participants with a history of COVID-19 or related symptoms were more likely to have positive IgG (P
AB - BACKGROUND: Since the occurrence of coronavirus disease in 2019 (COVID-19), the global community has witnessed its exponential spread with devastating outcomes within the general population and specifically within hemodialysis patients.
OBJECTIVES: Compare the state of immunity to SARS-CoV-2 among hemodialysis patients and staff.
DESIGN: Cross-sectional study with a prospective follow-up period.
SETTING: Hemodialysis centers in Madinah region.
PATIENTS AND METHODS: We prospectively tested for SARS-CoV-2 antibodies in dialysis patients using dialysis centers staff as controls. The participants were tested on four occasions when feasible for the presence of anti-SARS-CoV-2 antibodies. We also analyzed factors that might be associated with seropositivity.
MAIN OUTCOME MEASURES: SARS-CoV-2 positivity using immunoglobulin G (IgG) levels
SAMPLE SIZE: 830 participants, 677 patients and 153 dialysis centers staff as controls.
RESULTS: Of the total participants, 325 (257 patients and 68 staff) were positive for SARS-CoV-2 IgG antibodies, for a prevalence of 38.0% and 44.4% among patients and staff, respectively (P=.1379). Participants with a history of COVID-19 or related symptoms were more likely to have positive IgG (P
UR - http://hdl.handle.net/10754/680172
UR - http://www.annsaudimed.net/doi/10.5144/0256-4947.2022.229
U2 - 10.5144/0256-4947.2022.229
DO - 10.5144/0256-4947.2022.229
M3 - Article
C2 - 35933611
SN - 0256-4947
VL - 42
SP - 246
EP - 251
JO - Annals of Saudi Medicine
JF - Annals of Saudi Medicine
IS - 4
ER -