Pressure-driven enzyme entrapment in siliceous mesocellular foam

Yu Han, Su Seong Lee, Jackie Y. Ying*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

144 Scopus citations


A pressure-driven method was employed to immobilize enzymes on hydrophobic mesoporous silica supports. This approach gave rise to higher enzyme loading and reduced enzyme leaching, compared to conventional methods. Candida antarctica lipase B (CALB) was successfully entrapped in the cagelike pores of siliceous mesocellular foam using this method. The resulting supported enzyme catalyst demonstrated reusability and thermal stability superior to those of the commercial immobilized CALB catalyst, Novozyme 435.

Original languageEnglish (US)
Pages (from-to)643-649
Number of pages7
JournalChemistry of Materials
Issue number3
StatePublished - Feb 7 2006
Externally publishedYes

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering
  • Materials Chemistry


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