Abstract
In eukaryotes, most of the DNA is located in the nucleus where it is organized with histone proteins in a higher order structure as chromatin. Chromatin and chromatin-associated proteins contribute to DNA-related processes such as replication and transcription as well as epigenetic regulation. Protein functions are often regulated by PTMs among which phosphorylation is one of the most abundant PTM. Phosphorylation of proteins affects important properties, such as enzyme activity, protein stability, or subcellular localization. We here describe the main specificities of protein phosphorylation in plants and review the current knowledge on phosphorylation-dependent regulation of plant chromatin and chromatin-associated proteins. We also outline some future challenges to further elucidate protein phosphorylation and chromatin regulation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2127-2140 |
| Number of pages | 14 |
| Journal | PROTEOMICS |
| Volume | 14 |
| Issue number | 19 |
| DOIs | |
| State | Published - Jul 10 2014 |
Bibliographical note
KAUST Repository Item: Exported on 2020-10-01Acknowledgements: This work was supported by the Agence Nationale de la Recherche (ANR-2010-JCJC-1608 to D. P.) and the Laboratory of Excellence Saclay Plant Sciences. We apologize for not citing many other published reports because of space limitations.
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology