PARP1 Parylation Promotes Silent Locus Transmission in the Nucleolus: The Suspicion Confirmed

Maxim Isabelle; Imed Eddine Gallouzi; Guy G. Poirier

doi:10.1016/j.molcel.2012.03.012

PARP1 Parylation Promotes Silent Locus Transmission in the Nucleolus: The Suspicion Confirmed

Maxim Isabelle, Imed Eddine Gallouzi, Guy G. Poirier

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Parylation modulates various processes, including transcription. In this issue of Molecular Cell, Guetg et al. (2012) show that, in the nucleolus, PARP1-mediated parylation of TIP5 promotes the silencing of rDNA chromatin during replication, uncovering the mechanism by which PARP1 ensures that silent rDNA regions are properly inherited. © 2012 Elsevier Inc..

Original language	English (US)
Pages (from-to)	706-707
Number of pages	2
Journal	Molecular Cell
Volume	45
Issue number	6
DOIs	https://doi.org/10.1016/j.molcel.2012.03.012
State	Published - Mar 30 2012
Externally published	Yes

Bibliographical note

Generated from Scopus record by KAUST IRTS on 2022-09-13

ASJC Scopus subject areas

Cell Biology
Molecular Biology

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10.1016/j.molcel.2012.03.012

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AB - Parylation modulates various processes, including transcription. In this issue of Molecular Cell, Guetg et al. (2012) show that, in the nucleolus, PARP1-mediated parylation of TIP5 promotes the silencing of rDNA chromatin during replication, uncovering the mechanism by which PARP1 ensures that silent rDNA regions are properly inherited. © 2012 Elsevier Inc..

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PARP1 Parylation Promotes Silent Locus Transmission in the Nucleolus: The Suspicion Confirmed

Abstract

Bibliographical note

ASJC Scopus subject areas

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