Organic Bioelectronic Devices for Metabolite Sensing

Anil Koklu, David Ohayon, Shofarul Wustoni, Victor Druet, Abdulelah Saleh, Sahika Inal

Research output: Contribution to journalArticlepeer-review

53 Scopus citations


Electrochemical detection of metabolites is essential for early diagnosis and continuous monitoring of a variety of health conditions. This review focuses on organic electronic material-based metabolite sensors and highlights their potential to tackle critical challenges associated with metabolite detection. We provide an overview of the distinct classes of organic electronic materials and biorecognition units used in metabolite sensors, explain the different detection strategies developed to date, and identify the advantages and drawbacks of each technology. We then benchmark state-of-the-art organic electronic metabolite sensors by categorizing them based on their application area (in vitro, body-interfaced, in vivo, and cell-interfaced). Finally, we share our perspective on using organic bioelectronic materials for metabolite sensing and address the current challenges for the devices and progress to come.
Original languageEnglish (US)
JournalChemical Reviews
StatePublished - Oct 5 2021

Bibliographical note

KAUST Repository Item: Exported on 2021-10-08

ASJC Scopus subject areas

  • General Chemistry


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