Optimized fabrication protocols of microfluidic devices for X-ray analysis

Rossella Catalano, Gerardo Perozziello, Giuseppina Simone, Patrizio Candeloro, Francesco T. Gentile, Maria Laura Coluccio, Francesca Pardeo, Manfred C. Burghammer, Giovanni Cuda, Christian Riekel, Enzo M. Di Fabrizio

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Microfluidics combined with X-ray scattering techniques allows probing conformational changes or assembly processes of biological materials. Our aim was to develop a highly X-ray transparent microfluidic cell for detecting small variations of X-ray scattering involved in such processes. We describe the fabrication of a polyimide microfluidic device based on a simple, reliable and inexpensive lamination process. The implemented microstructured features result in windows with optimized X-ray transmission. The microfluidic device was characterized by X-ray microbeam scattering at the ID13 beamline of the European Synchrotron Radiation Facility. © 2014 Elsevier B.V. All rights reserved.
Original languageEnglish (US)
Pages (from-to)13-16
Number of pages4
JournalMicroelectronic Engineering
StatePublished - Jul 2014

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: This work was partially supported by the European project EUROMBR (grant agreement n. 608104), the project for Young Researchers financed from the Italian Ministry of Health (CUP J65C13001350001, project n. GR-2010-2311677) and the project FIRB "ReteNazionale di Ricerca sulle Nanoscienze ItalNanoNet" (cod. RBPR05JH2P_010, CUP B41J09000110005) granted to the nanotechnology laboratory of the Department of Experimental Medicine of the University of Catanzaro.

ASJC Scopus subject areas

  • Surfaces, Coatings and Films
  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering
  • Condensed Matter Physics


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