Optical local and superficial probing of tissues for in vivo diagnosis

Philippe Thueler*, Michel St Ghislain, Christian Depeursinge, Igor Charvet, Paolo Meda, Ben Vermeulen

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review


An optical tissue diagnosis technique, often called "optical biopsy", has been developed. It is based on the simultaneous determination of the optical properties of tissues such as the reduced scattering coefficient μs' and the absorption coefficient μa. These data are obtained by applying a small diameter probe (ø 2mm) on tissues, through the working channel of usual endoscopes. The simultaneous determination of μa and μs' with a local probe was made possible by the consideration of the first two moments of the phase function and a proven model of light propagation in tissues at propagation length comparable to the scattering mean free path. Non-invasive measurements of the optical coefficients of superficial tissues have been obtained in vivo at different wavelength.

Original languageEnglish (US)
Pages (from-to)266-271
Number of pages6
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - 2003
Externally publishedYes
EventDiagnostic Optical Spectroscopy in Biomedicine II - Munich, Germany
Duration: Jun 24 2003Jun 25 2003

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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