Optical local and superficial probing of tissues for in vivo diagnosis

Philippe Thueler; Michel St Ghislain; Christian Depeursinge; Igor Charvet; Paolo Meda; Ben Vermeulen

doi:10.1117/12.500831

Optical local and superficial probing of tissues for in vivo diagnosis

Philippe Thueler^*, Michel St Ghislain, Christian Depeursinge, Igor Charvet, Paolo Meda, Ben Vermeulen

^*Corresponding author for this work

Research output: Contribution to journal › Conference article › peer-review

Abstract

An optical tissue diagnosis technique, often called "optical biopsy", has been developed. It is based on the simultaneous determination of the optical properties of tissues such as the reduced scattering coefficient μ_s' and the absorption coefficient μ_a. These data are obtained by applying a small diameter probe (ø 2mm) on tissues, through the working channel of usual endoscopes. The simultaneous determination of μ_a and μ_s' with a local probe was made possible by the consideration of the first two moments of the phase function and a proven model of light propagation in tissues at propagation length comparable to the scattering mean free path. Non-invasive measurements of the optical coefficients of superficial tissues have been obtained in vivo at different wavelength.

Original language	English (US)
Pages (from-to)	266-271
Number of pages	6
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	5141
DOIs	https://doi.org/10.1117/12.500831
State	Published - 2003
Externally published	Yes
Event	Diagnostic Optical Spectroscopy in Biomedicine II - Munich, Germany Duration: Jun 24 2003 → Jun 25 2003

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.500831

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title = "Optical local and superficial probing of tissues for in vivo diagnosis",

abstract = "An optical tissue diagnosis technique, often called {"}optical biopsy{"}, has been developed. It is based on the simultaneous determination of the optical properties of tissues such as the reduced scattering coefficient μs' and the absorption coefficient μa. These data are obtained by applying a small diameter probe ({\o} 2mm) on tissues, through the working channel of usual endoscopes. The simultaneous determination of μa and μs' with a local probe was made possible by the consideration of the first two moments of the phase function and a proven model of light propagation in tissues at propagation length comparable to the scattering mean free path. Non-invasive measurements of the optical coefficients of superficial tissues have been obtained in vivo at different wavelength.",

author = "Philippe Thueler and Ghislain, {Michel St} and Christian Depeursinge and Igor Charvet and Paolo Meda and Ben Vermeulen",

year = "2003",

doi = "10.1117/12.500831",

language = "English (US)",

volume = "5141",

pages = "266--271",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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publisher = "SPIE",

note = "Diagnostic Optical Spectroscopy in Biomedicine II ; Conference date: 24-06-2003 Through 25-06-2003",

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TY - JOUR

T1 - Optical local and superficial probing of tissues for in vivo diagnosis

AU - Thueler, Philippe

AU - Ghislain, Michel St

AU - Depeursinge, Christian

AU - Charvet, Igor

AU - Meda, Paolo

AU - Vermeulen, Ben

PY - 2003

Y1 - 2003

N2 - An optical tissue diagnosis technique, often called "optical biopsy", has been developed. It is based on the simultaneous determination of the optical properties of tissues such as the reduced scattering coefficient μs' and the absorption coefficient μa. These data are obtained by applying a small diameter probe (ø 2mm) on tissues, through the working channel of usual endoscopes. The simultaneous determination of μa and μs' with a local probe was made possible by the consideration of the first two moments of the phase function and a proven model of light propagation in tissues at propagation length comparable to the scattering mean free path. Non-invasive measurements of the optical coefficients of superficial tissues have been obtained in vivo at different wavelength.

AB - An optical tissue diagnosis technique, often called "optical biopsy", has been developed. It is based on the simultaneous determination of the optical properties of tissues such as the reduced scattering coefficient μs' and the absorption coefficient μa. These data are obtained by applying a small diameter probe (ø 2mm) on tissues, through the working channel of usual endoscopes. The simultaneous determination of μa and μs' with a local probe was made possible by the consideration of the first two moments of the phase function and a proven model of light propagation in tissues at propagation length comparable to the scattering mean free path. Non-invasive measurements of the optical coefficients of superficial tissues have been obtained in vivo at different wavelength.

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U2 - 10.1117/12.500831

DO - 10.1117/12.500831

M3 - Conference article

AN - SCOPUS:1342310458

SN - 0277-786X

VL - 5141

SP - 266

EP - 271

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Diagnostic Optical Spectroscopy in Biomedicine II

Y2 - 24 June 2003 through 25 June 2003

ER -

Optical local and superficial probing of tissues for in vivo diagnosis

Abstract

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