Nickel-Catalyzed Synthesis of Silanes from Silyl Ketones

Watchara Srimontree; Waranya Lakornwong; Magnus Rueping

doi:10.1021/acs.orglett.9b03487

Nickel-Catalyzed Synthesis of Silanes from Silyl Ketones

Watchara Srimontree, Waranya Lakornwong, Magnus Rueping

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

An unprecedented nickel-catalyzed decarbonylative silylation via CO extrusion intramolecular recombination fragment coupling of unstrained and nondirecting group-Assisted silyl ketones is described. The inexpensive and readily available catalyst performs under mild reaction conditions and enables the synthesis of structurally diverse arylsilanes, including heterocyclic and natural product derivatives.

Original language	English (US)
Pages (from-to)	9330-9333
Number of pages	4
Journal	Organic Letters
Volume	21
Issue number	23
DOIs	https://doi.org/10.1021/acs.orglett.9b03487
State	Published - Nov 8 2019

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: W.L. was supported by the Thailand Research Fund through the Royal Golden Jubilee Ph.D. Program for the one-year exchange fellowship to RWTH-Aachen University. We thank Tengfei Ji for performing the large scale experiment.

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title = "Nickel-Catalyzed Synthesis of Silanes from Silyl Ketones",

abstract = "An unprecedented nickel-catalyzed decarbonylative silylation via CO extrusion intramolecular recombination fragment coupling of unstrained and nondirecting group-Assisted silyl ketones is described. The inexpensive and readily available catalyst performs under mild reaction conditions and enables the synthesis of structurally diverse arylsilanes, including heterocyclic and natural product derivatives.",

author = "Watchara Srimontree and Waranya Lakornwong and Magnus Rueping",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: W.L. was supported by the Thailand Research Fund through the Royal Golden Jubilee Ph.D. Program for the one-year exchange fellowship to RWTH-Aachen University. We thank Tengfei Ji for performing the large scale experiment.",

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doi = "10.1021/acs.orglett.9b03487",

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T1 - Nickel-Catalyzed Synthesis of Silanes from Silyl Ketones

AU - Srimontree, Watchara

AU - Lakornwong, Waranya

AU - Rueping, Magnus

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: W.L. was supported by the Thailand Research Fund through the Royal Golden Jubilee Ph.D. Program for the one-year exchange fellowship to RWTH-Aachen University. We thank Tengfei Ji for performing the large scale experiment.

PY - 2019/11/8

Y1 - 2019/11/8

N2 - An unprecedented nickel-catalyzed decarbonylative silylation via CO extrusion intramolecular recombination fragment coupling of unstrained and nondirecting group-Assisted silyl ketones is described. The inexpensive and readily available catalyst performs under mild reaction conditions and enables the synthesis of structurally diverse arylsilanes, including heterocyclic and natural product derivatives.

AB - An unprecedented nickel-catalyzed decarbonylative silylation via CO extrusion intramolecular recombination fragment coupling of unstrained and nondirecting group-Assisted silyl ketones is described. The inexpensive and readily available catalyst performs under mild reaction conditions and enables the synthesis of structurally diverse arylsilanes, including heterocyclic and natural product derivatives.

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UR - https://pubs.acs.org/doi/10.1021/acs.orglett.9b03487

UR - http://www.scopus.com/inward/record.url?scp=85074925001&partnerID=8YFLogxK

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SP - 9330

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JO - Organic Letters

JF - Organic Letters

IS - 23

ER -

Nickel-Catalyzed Synthesis of Silanes from Silyl Ketones

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